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NCT04906252 · ClinicalTrials.gov registry record
Vfib by ECG or Echo During Cardiac Arrest
A clinical trial of Cardiac Arrest, sponsored by Romolo Gaspari.
- Completed
- Registry status
- 813
- Enrollment target
- 6
- Study locations
NCT04906252: Completed study of Cardiac Arrest, sponsored by Romolo Gaspari.
NCT04906252 is a study of Cardiac Arrest that has completed, run by Romolo Gaspari. The registered enrollment target is 813 participants, below the 1,454-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (44% lower). The trial reports 6 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04906252, a study of Cardiac Arrest, has completed, sponsored by Romolo Gaspari.
- COMPLETED
- Registry status
- 813 participants
- Enrollment target
- 6
- Study locations
Study Summary
The goal of this study is to measure survival rates associated with patients presenting in cardiac arrest based on their electrocardiographic rhythm and their echocardiographic rhythm. Electrocardiographic rhythm is defined as the rhythm on the ECG and echocardiographic rhythm is the rhythm visualized on bedside ultrasound. Specifically, we will categorize patients based on identical rhythms and dichotomous rhythms with an interest in outcomes in the patient group where their echocardiographic and electrographic rhythms do not match. This is important as current ACLS protocols use electrocardiographic rhythms to determine therapy but limited research implies that therapeutic decisions based on echocardiographic rhythm may produce increased survival. This study will occur during emergency department resuscitation of patients presenting in cardiac arrest. Patients presenting to the emergency department after cardiac arrest will undergo standard resuscitation based on ACLS protocols. Ultrasound imaging will be performed as soon as possible after the patient arrives and digitally recorded, as is currently the standard of care at the institute. Simultaneous recording of the ECG rhythm strip will occur as well. This will be repeated for as many pauses in CPR as is warranted. Each site will record data based on the Utstein nomenclature including patient demographics, arrest details and survival outcomes. Ultrasound images and ECG recordings will be de-identified and submitted to a central database. Data will be uploaded into a centralized database. Statistical analysis will analyze outcomes based on echocardiographic and sonographic findings. Our aim is to measure the survival benefit of treating out of hospital cardiac arrest using echocardiographic rhythm instead of electrocardiographic rhythm.
Primary Outcome
Percentage of patients who survive at the point where they are admitted to the hospital
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Echocardiography
- DIAGNOSTIC_TEST Electrocardiogram (ECG)
Study Locations (6)
Connecticut
- Hartford Hospital - Hartford
New Hampshire
- Dartmouth Hitchcock Medical Center - Lebanon
New York
- Stony Brook University - Stony Brook
North Carolina
- Duke University - Durham
Pennsylvania
- Allegheny Hospital - Pittsburgh
Texas
- Univesity of Texas San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 813 participants |
| Start Date | 2021-09-15 |
| Est. Completion | 2025-01-01 |
What the finished NCT04906252 record still lists
NCT04906252 is an observational study that tracks outcomes without assigning an intervention. The registered 813 participants enrollment target is mid-sized for trials with a published cap, below the 1,454-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (44% lower).
The record links to 1 condition, with Cardiac Arrest appearing as the primary indexed condition, and to 2 interventions - of which Echocardiography is the first listed.
NCT04906252 lists 6 locations in 6 states (Connecticut, New Hampshire, New York).
Frequently Asked Questions
What is clinical trial NCT04906252 about?
NCT04906252 is a clinical study titled "Vfib by ECG or Echo During Cardiac Arrest". The goal of this study is to measure survival rates associated with patients presenting in cardiac arrest based on their electrocardiographic rhythm and their echocardiographic rhythm. Electrocardiographic rhythm is defined as the rhythm on the ECG and echocardiographic rhythm is the rhythm visualiz...
What is the current status of trial NCT04906252?
This trial is currently completed. The enrollment target is 813 participants. The study started on 2021-09-15. Estimated completion is 2025-01-01.
What conditions does trial NCT04906252 study?
This clinical trial studies the following conditions: Cardiac Arrest.
What interventions are being tested in trial NCT04906252?
The interventions under investigation include: Echocardiography (DIAGNOSTIC_TEST), Electrocardiogram (ECG) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04906252?
This trial is sponsored by Romolo Gaspari, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04906252 being conducted?
This trial has 6 study locations across Connecticut, New Hampshire, New York, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04906252's enrollment target sits among peer trials
813 7th of 31 higher than 25 of 31 other Cardiac Arrest trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Arrest trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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