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NCT06455514 · ClinicalTrials.gov registry record · Phase 1
Post-CA Neuroprotection With Magnesium
A Phase 1 study of Cardiac Arrest and Return of Spontaneous Circulation, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 178
- Enrollment target
- 1
- Study location
NCT06455514: Recruiting Phase 1 study of Cardiac Arrest and Return of Spontaneous Circulation, sponsored by NYU Langone Health.
NCT06455514 is a Phase 1 study of Cardiac Arrest and Return of Spontaneous Circulation that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 178 participants, below the 1,474-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06455514, a Phase 1 study of Cardiac Arrest and Return of Spontaneous Circulation, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 178 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac Arrest (CA). The primary aims are to assess the feasibility and safety of administering magnesium and measure serum markers of neuronal injury at prespecified time points in the post-cardiac arrest period. Because this is a pilot study with a limited sample size, the primary objective is to evaluate the precision and stability of the collected measures to inform the design and formal analysis in a larger trial.
Conditions Studied
Interventions
- DRUG Saline
- DRUG Magnesium Sulfate
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 178 participants |
| Start Date | 2025-03-25 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 1 |
What NCT06455514 shows while recruiting
NCT06455514 is an interventional study that assigns participants to a tested intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, below the 1,474-participant average among 31 other Cardiac Arrest trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Cardiac Arrest appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT06455514 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06455514 about?
NCT06455514 is a clinical study titled "Post-CA Neuroprotection With Magnesium". The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac Arrest (CA). The primary aims are to assess the feasibility and safety ...
What is the current status of trial NCT06455514?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 178 participants. The study started on 2025-03-25. Estimated completion is 2026-06-30.
What conditions does trial NCT06455514 study?
This clinical trial studies the following conditions: Cardiac Arrest, Return of Spontaneous Circulation.
What interventions are being tested in trial NCT06455514?
The interventions under investigation include: Saline (DRUG), Magnesium Sulfate (DRUG).
Who is sponsoring clinical trial NCT06455514?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06455514 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiac Arrest
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06455514's enrollment target sits among peer trials
178 15th of 31 higher than 17 of 31 other Cardiac Arrest trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Arrest trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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