Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING

Cannabis, HIV and Mental Processing Systems

NCT05430490 · View on ClinicalTrials.gov ↗

Study Summary

This study employs novel methods to identify key determinants and consequences of concurrent HIV infection and regular cannabis use. This study will acquire extensive phenotype data from peripheral and brain markers of immune activation, brain structure, and neuropsychological performance (NP) in persons living with HIV (PLWH) receiving combination anti-retroviral therapy (cART) (80 regular cannabis users and 80 non-users) and HIV uninfected (HIV-) controls (80 regular cannabis users and 80 non-users). This study will provide key insights into the effects of regular cannabis and HIV on peripheral and brain markers of immune function and NP in PLWH and HIV- controls. These insights are critical for cure strategies and ongoing HIV treatment initiatives.

Conditions Studied

Interventions

  • PROCEDURE Lumbar Puncture
  • OTHER Questionnaires
  • PROCEDURE Blood Draw
  • PROCEDURE MRI
  • OTHER NeuroPsychological Testing

Study Locations (2)

Missouri

  • Washington University School of Medicine — St Louis

New Jersey

  • Rutgers University — Newark

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2022-03-23
Est. Completion 2026-06-30

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05430490

The ClinicalTrials.gov registry entry for NCT05430490 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,036 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 5 interventions — of which Lumbar Puncture is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05430490 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Missouri, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05430490 about?

NCT05430490 is a clinical study titled "Cannabis, HIV and Mental Processing Systems". This study employs novel methods to identify key determinants and consequences of concurrent HIV infection and regular cannabis use. This study will acquire extensive phenotype data from peripheral and brain markers of immune activation, brain structure, and neuropsychological performance (NP) in pe...

What is the current status of trial NCT05430490?

This trial is currently recruiting. The enrollment target is 320 participants. The study started on 2022-03-23. Estimated completion is 2026-06-30.

What conditions does trial NCT05430490 study?

This clinical trial studies the following conditions: HIV Infections, Cannabis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05430490?

The interventions under investigation include: Lumbar Puncture (PROCEDURE), Questionnaires (OTHER), Blood Draw (PROCEDURE), MRI (PROCEDURE), NeuroPsychological Testing (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05430490?

This trial is sponsored by Washington University School of Medicine, which has 1,036 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05430490 being conducted?

This trial has 2 study locations across Missouri, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial