Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,963 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,963 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,963 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Open enrollment, early-phase tilt

Cancer has 621 registered US clinical trials, 279 of them open to new participants right now, about 45% of the total.

279
recruiting participants now
45%
of trials open to enrollment
31
in Phase 3-4 (later-stage)
31
top sponsor: M.D. Anderson Cancer Center

Corpus placement: #6 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 9 of 13

COMPLETED NA 485 participants

VOICE: Values and Options in Cancer Care

University of Rochester

NCT01485627

COMPLETED 481 participants

St. Jude Cancer Education for Children Program: Evaluation at 4th-Grade Level

St. Jude Children's Research Hospital

NCT01185093

COMPLETED NA 476 participants

Behavioral Economic Strategies to Improve PRO Adherence

Abramson Cancer Center at Penn Medicine

NCT06013176

COMPLETED NA 442 participants

Promoting Smoking Cessation in Carpenters

Washington University School of Medicine

NCT01878214

COMPLETED Phase 2 410 participants

Yoga in Treating Sleep Disturbance in Cancer Survivors

Gary Morrow

NCT00397930

COMPLETED NA 390 participants

Electronic Symptom Monitoring Intervention for Hospitalized Patients With Cancer

Massachusetts General Hospital

NCT03396510

COMPLETED Phase 3 384 participants

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

Amgen

NCT00838201

COMPLETED NA 374 participants

A Web Site and Print Materials Intervention for Smoking Intervention for Childhood and Young Adult Cancer Survivors

Dana-Farber Cancer Institute

NCT00588107

COMPLETED NA 354 participants

Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs

Medtronic Spinal and Biologics

NCT01871519

COMPLETED NA 352 participants

MOST EMPOWER: Optimizing An Emotion Regulation Intervention

Wake Forest University Health Sciences

NCT04317417

COMPLETED Phase 4 338 participants

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

Pfizer

NCT00942968

COMPLETED 314 participants

Black Family Eating Behaviors Study

National Human Genome Research Institute (NHGRI)

NCT02015078

COMPLETED 310 participants

Family Genetics Health Education and Healthy Behaviors

National Human Genome Research Institute (NHGRI)

NCT01498276

COMPLETED Phase 2 308 participants

A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy

gicare Pharma

NCT01926444

COMPLETED 300 participants

Microculture Kinetic (MiCK) Apoptosis Test Results With Drug Treatment Results in Cancer Patients

Pierian Biosciences

NCT00901264

COMPLETED 300 participants

Evaluation of Preexisting Immunity Markers in Human Tumor Tissue Sample

Stanford University

NCT00568867

COMPLETED 299 participants

F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases

Seattle Nuclear Medicine

NCT01254929

COMPLETED NA 286 participants

Care Transition Intervention for Hospitalized Patients With Advanced Cancer

Massachusetts General Hospital

NCT05142345

COMPLETED 282 participants

Sperm Banking Among Adolescents Newly Diagnosed With Cancer: Development of a Profiling and Referral Tool

St. Jude Children's Research Hospital

NCT01152268

COMPLETED 275 participants

Characterizing Lone Parenting: A Multi-institutional Pilot Study of the Perceptions of Support and Perceived Stress of Lone Parents of Children With Cancer

National Institute of Mental Health (NIMH)

NCT00969579

COMPLETED NA 266 participants

Consent Forms in Cancer Research: Examining the Effect of Length on Readability

Mayo Clinic

NCT04548063

COMPLETED NA 263 participants

Improving Cancer Patients' Insurance Choices

Washington University School of Medicine

NCT03592433

COMPLETED NA 260 participants

Building Evidence for Effective Palliative/End of Life Care for Teens With Cancer

Maureen Lyon

NCT02693665

COMPLETED NA 250 participants

Genome Sequencing of Human Cancer Tissues

New Mexico Cancer Research Alliance

NCT02105545

COMPLETED NA 245 participants

Genomic Medicine Risk Assessment Care for Everyone - Implementation Phase

Duke University

NCT06278883

COMPLETED Phase 3 244 participants

Study of the Safety of BEMA™ Fentanyl Use for Breakthrough Pain in Cancer Subjects on Chronic Opioid Therapy

BioDelivery Sciences International

NCT00293020

COMPLETED Phase 1 240 participants

A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT01633970

COMPLETED NA 237 participants

An Individualized Grief Intervention for Spouses of Cancer Patients After the Patient's Death

University of Utah

NCT02112084

COMPLETED Phase 1 214 participants

A Rollover Study to Provide Continued Treatment With GSK2118436 to Subjects With BRAF Mutation-Positive Tumors

Novartis Pharmaceuticals

NCT01231594

COMPLETED 213 participants

Accuracy of the D-Dimer Assay for the Exclusion of Pulmonary Embolism in a High Risk Oncologic Population

Memorial Sloan Kettering Cancer Center

NCT00615147

COMPLETED NA 209 participants

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

University of Alabama at Birmingham

NCT03767517

COMPLETED NA 206 participants

Treating Pain in Children With Cancer: Pain Buddy

University of California, Irvine

NCT03384134

COMPLETED NA 204 participants

Harnessing Generativity Among Young Adult Cancer Survivors

University of California, Los Angeles

NCT04272346

COMPLETED NA 200 participants

Do Self-Rated Performance Status Scores Correlate With Health-Care-Provider-Scores?

University of Florida

NCT00735111

COMPLETED 198 participants

Radiation Biodosimetry in Patients Treated With Total Body Irradiation (TBI)

Memorial Sloan Kettering Cancer Center

NCT00581958

COMPLETED Phase 1 190 participants

Study of JTX-8064, as Monotherapy and in Combination With a PD-1 Inhibitor, in Adult Subjects With Advanced Refractory Solid Tumors

Jounce Therapeutics

NCT04669899

COMPLETED NA 188 participants

A Brief Patient-Controlled Intervention for a Symptom Cluster in Advanced Cancer

University of Wisconsin, Madison

NCT01954420

COMPLETED 178 participants

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

National Institute of Environmental Health Sciences (NIEHS)

NCT01143519

COMPLETED Phase 1 176 participants

Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors

TetraLogic Pharmaceuticals

NCT01188499

COMPLETED 171 participants

Association Between Cancer and Sarcoidosis

University of Miami

NCT03844698

COMPLETED Phase 1 170 participants

A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors

GlaxoSmithKline

NCT00880321

COMPLETED NA 163 participants

Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds

Medical University of South Carolina

NCT02638298

COMPLETED NA 160 participants

Lay Health Worker Engage, Educate, and Encourage Patients to Share

Stanford University

NCT03699748

COMPLETED NA 160 participants

Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy

Memorial Sloan Kettering Cancer Center

NCT02356575

COMPLETED NA 150 participants

Pilot Study of a Symptom Monitoring Intervention for Hospitalized Patients With Cancer

Massachusetts General Hospital

NCT02891993

COMPLETED NA 150 participants

Calm for Cancer Sleep Disturbance

Arizona State University

NCT04345068

COMPLETED Phase 1 147 participants

A Study of BBI608 and BBI503 Administered in Combination to Adult Patients With Advanced Solid Tumors

Sumitomo Pharma America

NCT02432326

COMPLETED Phase 3 146 participants

An Intervention to Improve Outcomes in Patients With Advanced Cancer

Yale University

NCT01272024

COMPLETED Phase 1 141 participants

Study to Evaluate Safety & Tolerability of BMS-906024 in Combination With Chemotherapy & to Define DLTs & MTD of BMS-906024 in Combination With One of the Following Chemotherapy Regimens; Weekly Paclitaxel, 5FU+Irinotecan or Carboplatin+Paclitaxel in Subjects With Advanced / Metastatic Solid Tumors

Bristol-Myers Squibb

NCT01653470

COMPLETED NA 130 participants

Impact of Resistance Training-Protein Supplementation on Lean Muscle Mass in Childhood Cancer Survivors

St. Jude Children's Research Hospital

NCT02501460

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Cancer right now

279 recruiting of 621 indexed (45% open).

Phase mix: 31 late (III/IV) vs 164 early (I/II) (early-phase heavy).

Top sponsor: M.D. Anderson Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first. #6 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Cancer?

PlainTrial tracks 621 US clinical trials for Cancer, of which 279 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.