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COMPLETED Phase 1

A Study of BBI608 and BBI503 Administered in Combination to Adult Patients With Advanced Solid Tumors

NCT02432326 · View on ClinicalTrials.gov ↗

Study Summary

This is an open label, multi-center, phase 1 study of BBI608 and BBI503 administered orally in combination to patients with advanced solid tumors. The primary goal is to determine the safety, tolerability, and recommended phase II dose (RP2D) of the combination regimen.

Interventions

  • DRUG BBI608
  • DRUG BBI503

Study Locations (11)

Texas

  • Texas Oncology - Austin Midtown — Austin
  • Texas Oncology - Baylor Charles A. Sammons Cancer Center — Dallas
  • Texas Oncology - Fort Worth 12th Ave — Fort Worth
  • Texas Oncology, P.A. — San Antonio
  • Texas Oncology, P.A. — San Antonio
  • Texas Oncology - Tyler — Tyler

Illinois

  • University of Chicago Medicine Comprehensive Cancer Center — Chicago

Indiana

  • Indiana University Simon Cancer Center — Indianapolis

New York

  • Weill Cornell Medical College — New York

Virginia

  • Virginia Cancer Specialists, PC — Fairfax

Washington

  • Northwest Cancer Specialists, PC — Vancouver

Trial Details

FieldValue
Enrollment Target 147 participants
Start Date 2015-04
Est. Completion 2020-04
Phase Phase 1

Sponsor

Sumitomo Pharma America

65 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02432326

The ClinicalTrials.gov registry entry for NCT02432326 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 147 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sumitomo Pharma America, which has 65 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Cancer appearing as the primary indexed condition, and to 2 interventions — of which BBI608 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02432326 reports 11 study locations spanning 6 distinct geographic areas — top geographies include Texas, Illinois, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02432326 about?

NCT02432326 is a clinical study titled "A Study of BBI608 and BBI503 Administered in Combination to Adult Patients With Advanced Solid Tumors". This is an open label, multi-center, phase 1 study of BBI608 and BBI503 administered orally in combination to patients with advanced solid tumors. The primary goal is to determine the safety, tolerability, and recommended phase II dose (RP2D) of the combination regimen.

What is the current status of trial NCT02432326?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 147 participants. The study started on 2015-04. Estimated completion is 2020-04.

What conditions does trial NCT02432326 study?

This clinical trial studies the following conditions: Cancer, Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02432326?

The interventions under investigation include: BBI608 (DRUG), BBI503 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02432326?

This trial is sponsored by Sumitomo Pharma America, which has 65 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02432326 being conducted?

This trial has 11 study locations across Illinois, Indiana, New York, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial