Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Attention Deficit Hyperactivity Disorder clinical trials
23 of 89 indexed Attention Deficit Hyperactivity Disorder trials are currently recruiting.
89 US clinical trials · 23 currently recruiting
Attention Deficit Hyperactivity Disorder is the subject of 89 registered US clinical trials on ClinicalTrials.gov, 23 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 8 of these trials.
The research picture
Attention Deficit Hyperactivity Disorder has 89 registered US clinical trials, 23 of them open to new participants right now, about 26% of the total.
- 23
- recruiting participants now
- 26%
- of trials open to enrollment
- 21
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
89 total, page 2 of 2
Helping College Students With ADHD Lead Healthier Lifestyles
University of Maryland, College Park
NCT02829970
Bupropion for ADHD in Adolescents With Substance Use Disorder
University of Colorado, Denver
NCT00936299
New Technologies to Help Manage ADHD
Children's Hospital Medical Center, Cincinnati
NCT02390791
Cognitive ADHD Videogame Exploratory Study
Akili Interactive Labs
NCT01943539
dHealth Solution for Improving Parent Adherence to Behavioral Treatment for ADHD
University of California, San Francisco
NCT04025814
Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials
Massachusetts General Hospital
NCT01063153
Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
Denver Health and Hospital Authority
NCT00399763
PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations
Aevi Genomic Medicine, LLC, a Cerecor company
NCT03265119
Mindfulness-Based ADHD Treatment for Children: a Feasibility Study
Yale University
NCT04737512
A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall
NYU Langone Health
NCT00468143
Safety and Efficacy of Switching From a Stimulant Medication to Atomoxetine in Children and Adolescents With ADHD
Eli Lilly and Company
NCT00485875
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children
NYU Langone Health
NCT04108273
Naturalistic Substitution of Concerta in Adult Subject With ADHD Receiving Immediate Release Methylphenidate
Massachusetts General Hospital
NCT00302406
Mindful Parenting and Parent Training Program Study
New York University
NCT03796663
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
NYU Langone Health
NCT03148782
Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD
Children's Hospital Medical Center, Cincinnati
NCT02874690
Effectiveness and Duration of Effect of Open Treatment in Attention Deficit Hyperactivity Disorder (ADHD) Patients Treated With Lisdexamfetamine Dimesylate(Vyvanse)
NYU Langone Health
NCT01070394
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
University of Nebraska
NCT03730194
Attention-Deficit/Hyperactivity Disorder (ADHD) Brain Activity Changes to Psychostimulants
Hartford Hospital
NCT01310439
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
Massachusetts General Hospital
NCT04569058
Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT
NYU Langone Health
NCT02635035
Study of Medication Patch to Treat Children Ages 6-12 With ADHD
Massachusetts General Hospital
NCT00586157
Text Messaging Adherence to Stimulant Medication
Massachusetts General Hospital
NCT01967485
Mobile Behavioral Parent Training for Childhood ADHD: A Micro-randomized Trial
Florida International University
NCT06012851
A Safety and Effectiveness Study of JNJ-31001074 in Adults With Attention-Deficit/Hyperactivity Disorder.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00566449
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
University of Cincinnati
NCT00414921
Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory
Children's Hospital of Philadelphia
NCT00530257
Electroencephalogram (EEG) Study of Inattention Following Treatment With AKL-T01
Akili Interactive Labs
NCT03844269
Task-Based Grounding Program
Dartmouth-Hitchcock Medical Center
NCT04648553
Effects of Exercise Intensity on ADHD Symptoms
Kent State University
NCT06753253
Effectiveness Study of Videoconferencing on Teaching Parent Training Skills to Parents of Children With Attention Deficit Hyperactivity Disorder (ADHD)
University of California, Davis
NCT01161719
GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs
CogCubed
NCT01808066
Study of Droxidopa Treatment in Adults With Attention Deficit Hyperactivity Disorder With Co-administration of Carbidopa
Chelsea Therapeutics
NCT00983814
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices in Adults
CogCubed
NCT02127931
Lisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
Shire
NCT01010750
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
University of Oklahoma
NCT00541346
Medication Integration in Treatment of Comorbid Adolescent Substance Users/Attention Deficit Hyperactivity Disorder
The National Center on Addiction and Substance Abuse at Columbia University
NCT01369459
Healing Minds: Biofeedback and Breathing Practices in Children and Adolescents With ADHD
Hoskinson Health and Wellness Clinic
NCT06648252
Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder
Texas Tech University
NCT03533556
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 12 |
| Phase 3 | 7 |
| Phase 4 | 14 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Attention Deficit Hyperactivity Disorder Trial Landscape
89 indexed Attention Deficit Hyperactivity Disorder studies · 23 recruiting (26%).
Phase mix: 21 late (III/IV) vs 19 early (I/II).
Top sponsor: Massachusetts General Hospital (8 trials), 9 others listed. 39 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Attention Deficit Hyperactivity Disorder?
PlainTrial tracks 89 US clinical trials for Attention Deficit Hyperactivity Disorder, of which 23 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Attention Deficit Hyperactivity Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.