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NCT03935646 · ClinicalTrials.gov registry record · Phase 2

Acute Effects of Stimulant Medication in College Students With ADHD

A Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood, sponsored by University of Wyoming.

Recruiting
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT03935646 is a Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood that is actively recruiting participants, run by University of Wyoming. The registered enrollment target is 40 participants, below the 206-participant average among 88 other Attention Deficit Hyperactivity Disorder trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03935646, a Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood, is actively recruiting participants, sponsored by University of Wyoming.

RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent stimulant misuse among college students without ADHD. The working hypothesis is that stimulants, compared to baseline and placebo conditions, will improve executive functioning for college students with ADHD but not for college students without ADHD. Improvements on executive functioning measures (e.g., CPT-IP, Spatial Span) will be examined through 2 (ADHD vs. non-ADHD) x 3 (Baseline, Placebo, Stimulant) repeated measures ANOVAs. Follow-up analyses will include paired comparisons. Expected outcomes are to confirm these hypotheses and demonstrate the need for further study of stimulants. If confirmed, the results will provide pilot data for a larger NIH grant proposal aimed at further examining the acute effects of stimulants (i.e., improved cognitive functioning with stimulants) and comparing them to the acute effects of physical exercise (i.e., improved cognitive functioning immediately after exercise). The investigators expect this outcome to have an important positive impact because it can help support stimulant medication as an effective treatment for college students with ADHD (DuPaul et al., 2012). Additionally, demonstration that stimulants do not improve executive functioning for college students without ADHD can be used to help prevent and discourage stimulant misuse and diversion on college campuses (Hartung et al., 2013).

Interventions

  • DRUG Placebo
  • DRUG Adderall IR 10mg

Study Locations (1)

Wyoming

  • University of Wyoming - Laramie

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-02-11
Est. Completion 2025-06-30
Phase Phase 2

Sponsor

University of Wyoming

15 total trials

What the Registry Record Tells You About NCT03935646

The ClinicalTrials.gov registry entry for NCT03935646 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 206-participant average among 88 other Attention Deficit Hyperactivity Disorder trials with a reported enrollment target (81% lower). The listed sponsor is University of Wyoming, which has 15 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Attention Deficit Hyperactivity Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03935646 reports 1 study location spanning 1 distinct geographic area - top geographies include Wyoming.

Frequently Asked Questions

What is clinical trial NCT03935646 about?

NCT03935646 is a clinical study titled "Acute Effects of Stimulant Medication in College Students With ADHD". The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent stimulant misuse among college students without ADHD. The working hypothesi...

What is the current status of trial NCT03935646?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2020-02-11. Estimated completion is 2025-06-30.

What conditions does trial NCT03935646 study?

This clinical trial studies the following conditions: Attention Deficit Hyperactivity Disorder, Mood, Stimulant Use, Working Memory, Change in Sustained Attention.

What interventions are being tested in trial NCT03935646?

The interventions under investigation include: Placebo (DRUG), Adderall IR 10mg (DRUG).

Who is sponsoring clinical trial NCT03935646?

This trial is sponsored by University of Wyoming, which has 15 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03935646 being conducted?

This trial has 1 study location across Wyoming. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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