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NCT03935646 · ClinicalTrials.gov registry record · Phase 2
Acute Effects of Stimulant Medication in College Students With ADHD
A Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood, sponsored by University of Wyoming.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT03935646: Recruiting Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood, sponsored by University of Wyoming.
NCT03935646 is a Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood that is actively recruiting participants, run by University of Wyoming. The registered enrollment target is 40 participants, below the 216-participant average among 102 other Attention Deficit Hyperactivity Disorder trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03935646, a Phase 2 study of Attention Deficit Hyperactivity Disorder and Mood, is actively recruiting participants, sponsored by University of Wyoming.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent stimulant misuse among college students without ADHD. The working hypothesis is that stimulants, compared to baseline and placebo conditions, will improve executive functioning for college students with ADHD but not for college students without ADHD. Improvements on executive functioning measures (e.g., CPT-IP, Spatial Span) will be examined through 2 (ADHD vs. non-ADHD) x 3 (Baseline, Placebo, Stimulant) repeated measures ANOVAs. Follow-up analyses will include paired comparisons. Expected outcomes are to confirm these hypotheses and demonstrate the need for further study of stimulants. If confirmed, the results will provide pilot data for a larger NIH grant proposal aimed at further examining the acute effects of stimulants (i.e., improved cognitive functioning with stimulants) and comparing them to the acute effects of physical exercise (i.e., improved cognitive functioning immediately after exercise). The investigators expect this outcome to have an important positive impact because it can help support stimulant medication as an effective treatment for college students with ADHD (DuPaul et al., 2012). Additionally, demonstration that stimulants do not improve executive functioning for college students without ADHD can be used to help prevent and discourage stimulant misuse and diversion on college campuses (Hartung et al., 2013).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Adderall IR 10mg
Study Locations (1)
Wyoming
- University of Wyoming - Laramie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2020-02-11 |
| Est. Completion | 2025-06-30 |
| Phase | Phase 2 |
What NCT03935646 shows while recruiting
NCT03935646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 216-participant average among 102 other Attention Deficit Hyperactivity Disorder trials with a reported enrollment target (81% lower).
The record links to 5 conditions, with Attention Deficit Hyperactivity Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03935646 reports a single indexed study location in Wyoming.
Frequently Asked Questions
What is clinical trial NCT03935646 about?
NCT03935646 is a clinical study titled "Acute Effects of Stimulant Medication in College Students With ADHD". The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent stimulant misuse among college students without ADHD. The working hypothesi...
What is the current status of trial NCT03935646?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2020-02-11. Estimated completion is 2025-06-30.
What conditions does trial NCT03935646 study?
This clinical trial studies the following conditions: Attention Deficit Hyperactivity Disorder, Mood, Stimulant Use, Working Memory, Change in Sustained Attention.
What interventions are being tested in trial NCT03935646?
The interventions under investigation include: Placebo (DRUG), Adderall IR 10mg (DRUG).
Who is sponsoring clinical trial NCT03935646?
This trial is sponsored by University of Wyoming, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03935646 being conducted?
This trial has 1 study location across Wyoming. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03935646's enrollment target sits among peer trials
40 67th of 102 higher than 32 of 102 other Attention Deficit Hyperactivity Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Attention Deficit Hyperactivity Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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