Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Atopic Dermatitis clinical trials
55 of 151 indexed Atopic Dermatitis trials are currently recruiting.
151 US clinical trials · 55 currently recruiting
Atopic Dermatitis is the subject of 151 registered US clinical trials on ClinicalTrials.gov, 55 of them currently open to new participants. 47 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 10 of these trials.
The research picture
Atopic Dermatitis has 151 registered US clinical trials, 55 of them open to new participants right now, about 36% of the total.
- 55
- recruiting participants now
- 36%
- of trials open to enrollment
- 47
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Pfizer
Active & Recent Trials
151 total, page 2 of 4
Ethnic Differences in Mechanisms of Action of Dupilumab
University of Michigan
NCT05268107
Topical Treatment for Atopic Dermatitis
Wake Forest University Health Sciences
NCT06244212
Dupilumab De-escalation in Pediatric Atopic Dermatitis
Johns Hopkins University
NCT06116526
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT07262983
Molecular Signatures of Cutaneous Dupilumab Response
University of California, San Francisco
NCT05858619
A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
Target PharmaSolutions
NCT03661866
10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus
Bausch Health Americas
NCT00568997
A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05882877
Systems Biology of Early Atopy
National Institute of Allergy and Infectious Diseases (NIAID)
NCT04798079
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
AbbVie
NCT03568318
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)
Regeneron Pharmaceuticals
NCT02612454
Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis
Northwestern University
NCT01782703
A Study Evaluating APG777 in Atopic Dermatitis
Apogee Therapeutics
NCT06395948
Seal, Stopping Eczema and Allergy Study
Kari Nadeau, MD, PhD
NCT03742414
A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT05559359
Phase 2 Trial of HY209gel in Atopic Dermatitis Patients
Shaperon
NCT06024499
A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema
Pfizer
NCT07216027
A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis
Amgen
NCT06224192
A Study of Barzolvolimab in Patients With Atopic Dermatitis
Celldex Therapeutics
NCT06727552
Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
Q32 Bio
NCT05509023
A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis
AbbVie
NCT06718101
Tralokinumab for Dupilumab Failures
Psoriasis Treatment Center of Central New Jersey
NCT06773455
A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants
Pfizer
NCT07190430
Bodewell Products for the Treatment of Atopic Dermatitis
University of Alabama at Birmingham
NCT05566262
Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
Northwestern University
NCT03051347
Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)
AbbVie
NCT03569293
A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05724199
Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Regeneron Pharmaceuticals
NCT02260986
A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)
Amgen
NCT05651711
B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis
AOBiome
NCT04490109
A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Amgen
NCT05704738
Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis
Eli Lilly and Company
NCT04178967
Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)
Eli Lilly and Company
NCT04146363
Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index
Northwestern University
NCT00879944
Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults
Organon and
NCT05014568
Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)
Organon and
NCT05032859
Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
Regeneron Pharmaceuticals
NCT01859988
Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients
DS Biopharma
NCT02864498
Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).
LEO Pharma
NCT03526861
Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis
University of Southern California
NCT03981926
A Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT03443024
A Phase 2 Study of CIM331 for Atopic Dermatitis Patients
Chugai Pharmaceutical
NCT01986933
A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis
Incyte Corporation
NCT06238817
A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy
LEO Pharma
NCT05958407
Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.
Eli Lilly and Company
NCT04250337
A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
Amgen
NCT05899816
Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis
Eli Lilly and Company
NCT04250350
Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)
Nucryst Pharmaceuticals
NCT00076375
Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis
Vanda Pharmaceuticals
NCT02651714
An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis
PreCision Dermatology
NCT01826461
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 18 |
| Phase 2 | 48 |
| Phase 3 | 28 |
| Phase 4 | 19 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Atopic Dermatitis Trial Landscape
151 indexed Atopic Dermatitis studies · 55 recruiting (36%).
Phase mix: 47 late (III/IV) vs 66 early (I/II).
Top sponsor: Pfizer (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Atopic Dermatitis?
PlainTrial tracks 151 US clinical trials for Atopic Dermatitis, of which 55 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Atopic Dermatitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.