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ClinicalTrials.gov 55 recruiting now full pipeline #76 of 28,707 conditions

Atopic Dermatitis: full-pipeline trial registry

55 of 151 indexed Atopic Dermatitis trials are currently recruiting.

Corpus placement: #76 of 28,707 conditions by registered trial count.

151 US clinical trials · 55 currently recruiting · #76 of 28,707 conditions by registered trial count

Atopic Dermatitis: 151 US clinical trials tracked, 55 recruiting.

Atopic Dermatitis is the subject of 151 registered US clinical trials on ClinicalTrials.gov, 55 of them currently open to new participants. 47 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 10 of these trials.

Enrollment posture brief

Registry condition atopic-dermatitis

OPEN 55 | RECR 36% | LATE 47 | EARLY 66 | RANK #76 | SPON 10

Nearest open-share peer: Acquired Brain Injury (36% recruiting · 11 trials)

Cervical Cancer48.3%Sleep48%Insomnia40.8%Atopic Dermatitis (this)36%Alzheimers Disease23.3%
Open-enrollment share among volume-matched conditions near Atopic Dermatitis

Atopic Dermatitis lists 55 open slots (36% of 151 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Atopic Dermatitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Atopic Dermatitis recruits in line with its size-band peers.

    55 of 151 indexed trials (36.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Atopic Dermatitis trials is spread across many organizations.

    Pfizer accounts for 10 of 151 trials (6.6%). 80 distinct sponsors appear on at least one study for this condition label.

  3. Typical Atopic Dermatitis enrolment sits around 137 participants.

    Median target enrolment is 137 among the 151 trials that report a genuine target (sentinel values excluded). 65 of those (43%) plan for fewer than 100 participants.

  4. Atopic Dermatitis research is mostly interventional.

    122 interventional and 29 observational studies make up this index (80.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 118Phase 248Phase 328Phase 419

Open and recent trials

151 total, page 2 of 4

RECRUITING Phase 4 30 participants

Ethnic Differences in Mechanisms of Action of Dupilumab

University of Michigan

NCT05268107

RECRUITING NA 30 participants

Topical Treatment for Atopic Dermatitis

Wake Forest University Health Sciences

NCT06244212

RECRUITING Phase 4 30 participants

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Johns Hopkins University

NCT06116526

RECRUITING Phase 1 20 participants

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT07262983

RECRUITING Phase 4 15 participants

Molecular Signatures of Cutaneous Dupilumab Response

University of California, San Francisco

NCT05858619

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING 8,000 participants

10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus

Bausch Health Americas

NCT00568997

ACTIVE NOT RECRUITING Phase 3 2,621 participants

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05882877

ACTIVE NOT RECRUITING 2,500 participants

Systems Biology of Early Atopy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04798079

ACTIVE NOT RECRUITING Phase 3 1,533 participants

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

AbbVie

NCT03568318

ACTIVE NOT RECRUITING Phase 3 880 participants

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Regeneron Pharmaceuticals

NCT02612454

ACTIVE NOT RECRUITING 505 participants

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Northwestern University

NCT01782703

ACTIVE NOT RECRUITING Phase 2 470 participants

A Study Evaluating APG777 in Atopic Dermatitis

Apogee Therapeutics

NCT06395948

ACTIVE NOT RECRUITING Phase 2 398 participants

Seal, Stopping Eczema and Allergy Study

Kari Nadeau, MD, PhD

NCT03742414

ACTIVE NOT RECRUITING Phase 3 367 participants

A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT05559359

ACTIVE NOT RECRUITING Phase 2 210 participants

Phase 2 Trial of HY209gel in Atopic Dermatitis Patients

Shaperon

NCT06024499

ACTIVE NOT RECRUITING Phase 2 200 participants

A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

Pfizer

NCT07216027

ACTIVE NOT RECRUITING Phase 3 151 participants

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis

Amgen

NCT06224192

ACTIVE NOT RECRUITING Phase 2 131 participants

A Study of Barzolvolimab in Patients With Atopic Dermatitis

Celldex Therapeutics

NCT06727552

ACTIVE NOT RECRUITING Phase 2 102 participants

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Q32 Bio

NCT05509023

ACTIVE NOT RECRUITING Phase 2 83 participants

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

AbbVie

NCT06718101

ACTIVE NOT RECRUITING Phase 4 20 participants

Tralokinumab for Dupilumab Failures

Psoriasis Treatment Center of Central New Jersey

NCT06773455

ACTIVE NOT RECRUITING Phase 1 16 participants

A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants

Pfizer

NCT07190430

ACTIVE NOT RECRUITING Phase 4 15 participants

Bodewell Products for the Treatment of Atopic Dermatitis

University of Alabama at Birmingham

NCT05566262

COMPLETED NA 943 participants

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

Northwestern University

NCT03051347

COMPLETED Phase 3 912 participants

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

AbbVie

NCT03569293

COMPLETED Phase 3 746 participants

A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05724199

COMPLETED Phase 3 740 participants

Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT02260986

COMPLETED Phase 3 726 participants

A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

Amgen

NCT05651711

COMPLETED Phase 2 547 participants

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

AOBiome

NCT04490109

COMPLETED Phase 3 532 participants

A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05704738

COMPLETED Phase 3 445 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis

Eli Lilly and Company

NCT04178967

COMPLETED Phase 3 424 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)

Eli Lilly and Company

NCT04146363

COMPLETED 409 participants

Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index

Northwestern University

NCT00879944

COMPLETED Phase 3 407 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults

Organon and

NCT05014568

COMPLETED Phase 3 406 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)

Organon and

NCT05032859

COMPLETED Phase 2 380 participants

Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT01859988

COMPLETED Phase 2 321 participants

Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients

DS Biopharma

NCT02864498

COMPLETED Phase 3 301 participants

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

LEO Pharma

NCT03526861

COMPLETED NA 300 participants

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

University of Southern California

NCT03981926

COMPLETED Phase 2 280 participants

A Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT03443024

COMPLETED Phase 2 264 participants

A Phase 2 Study of CIM331 for Atopic Dermatitis Patients

Chugai Pharmaceutical

NCT01986933

COMPLETED Phase 3 241 participants

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

Incyte Corporation

NCT06238817

COMPLETED Phase 3 235 participants

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

LEO Pharma

NCT05958407

COMPLETED Phase 3 228 participants

Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.

Eli Lilly and Company

NCT04250337

COMPLETED Phase 3 221 participants

A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)

Amgen

NCT05899816

COMPLETED Phase 3 206 participants

Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT04250350

COMPLETED Phase 2 180 participants

Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)

Nucryst Pharmaceuticals

NCT00076375

COMPLETED Phase 2 168 participants

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

Vanda Pharmaceuticals

NCT02651714

COMPLETED Phase 2 151 participants

An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis

PreCision Dermatology

NCT01826461

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 48
Phase 3 28
Phase 4 19

Named interventions

Most-linked intervention names on Atopic Dermatitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
32 trials
Placebo Other
13 trials
Dupilumab Drug
8 trials
Lebrikizumab Biological
5 trials
Rocatinlimab Drug
5 trials
Abrocitinib Drug
4 trials
Crisaborole Drug
3 trials
Vehicle Cream Drug
3 trials

US sites by state

Facility locations filed on Atopic Dermatitis trials. A trial with sites in several states counts in each.

California 88 trials
Florida 66 trials
New York 38 trials
Alabama 36 trials
Illinois 33 trials
Arizona 33 trials
Texas 32 trials
Arkansas 32 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Atopic Dermatitis page

151 registered trials, 55 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 55 Atopic Dermatitis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Pfizer sponsors the most Atopic Dermatitis trials on record, review their full trial history before evaluating a specific study. See Pfizer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atopic Dermatitis condition card totals 151 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.