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ClinicalTrials.gov 55 recruiting now official registry

Atopic Dermatitis clinical trials

55 of 151 indexed Atopic Dermatitis trials are currently recruiting.

151 US clinical trials · 55 currently recruiting

Atopic Dermatitis is the subject of 151 registered US clinical trials on ClinicalTrials.gov, 55 of them currently open to new participants. 47 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 10 of these trials.

The research picture

Atopic Dermatitis has 151 registered US clinical trials, 55 of them open to new participants right now, about 36% of the total.

55
recruiting participants now
36%
of trials open to enrollment
47
in Phase 3–4 (later-stage)
10
top sponsor: Pfizer
Phase 118Phase 248Phase 328Phase 419

Active & Recent Trials

151 total, page 2 of 4

RECRUITING Phase 4 30 participants

Ethnic Differences in Mechanisms of Action of Dupilumab

University of Michigan

NCT05268107

RECRUITING NA 30 participants

Topical Treatment for Atopic Dermatitis

Wake Forest University Health Sciences

NCT06244212

RECRUITING Phase 4 30 participants

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Johns Hopkins University

NCT06116526

RECRUITING Phase 1 20 participants

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT07262983

RECRUITING Phase 4 15 participants

Molecular Signatures of Cutaneous Dupilumab Response

University of California, San Francisco

NCT05858619

ACTIVE NOT RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

Target PharmaSolutions

NCT03661866

ACTIVE NOT RECRUITING 8,000 participants

10 Year Registry of Children (Ages 2-17 Years) With Eczema That Have Used Pimecrolimus

Bausch Health Americas

NCT00568997

ACTIVE NOT RECRUITING Phase 3 2,621 participants

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05882877

ACTIVE NOT RECRUITING 2,500 participants

Systems Biology of Early Atopy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT04798079

ACTIVE NOT RECRUITING Phase 3 1,533 participants

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

AbbVie

NCT03568318

ACTIVE NOT RECRUITING Phase 3 880 participants

Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD)

Regeneron Pharmaceuticals

NCT02612454

ACTIVE NOT RECRUITING 505 participants

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Northwestern University

NCT01782703

ACTIVE NOT RECRUITING Phase 2 470 participants

A Study Evaluating APG777 in Atopic Dermatitis

Apogee Therapeutics

NCT06395948

ACTIVE NOT RECRUITING Phase 2 398 participants

Seal, Stopping Eczema and Allergy Study

Kari Nadeau, MD, PhD

NCT03742414

ACTIVE NOT RECRUITING Phase 3 367 participants

A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT05559359

ACTIVE NOT RECRUITING Phase 2 210 participants

Phase 2 Trial of HY209gel in Atopic Dermatitis Patients

Shaperon

NCT06024499

ACTIVE NOT RECRUITING Phase 2 200 participants

A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

Pfizer

NCT07216027

ACTIVE NOT RECRUITING Phase 3 151 participants

A Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopic Dermatitis

Amgen

NCT06224192

ACTIVE NOT RECRUITING Phase 2 131 participants

A Study of Barzolvolimab in Patients With Atopic Dermatitis

Celldex Therapeutics

NCT06727552

ACTIVE NOT RECRUITING Phase 2 102 participants

Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)

Q32 Bio

NCT05509023

ACTIVE NOT RECRUITING Phase 2 83 participants

A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis

AbbVie

NCT06718101

ACTIVE NOT RECRUITING Phase 4 20 participants

Tralokinumab for Dupilumab Failures

Psoriasis Treatment Center of Central New Jersey

NCT06773455

ACTIVE NOT RECRUITING Phase 1 16 participants

A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants

Pfizer

NCT07190430

ACTIVE NOT RECRUITING Phase 4 15 participants

Bodewell Products for the Treatment of Atopic Dermatitis

University of Alabama at Birmingham

NCT05566262

COMPLETED NA 943 participants

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

Northwestern University

NCT03051347

COMPLETED Phase 3 912 participants

Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema)

AbbVie

NCT03569293

COMPLETED Phase 3 746 participants

A Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitors in Adult Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05724199

COMPLETED Phase 3 740 participants

Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT02260986

COMPLETED Phase 3 726 participants

A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

Amgen

NCT05651711

COMPLETED Phase 2 547 participants

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

AOBiome

NCT04490109

COMPLETED Phase 3 532 participants

A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Amgen

NCT05704738

COMPLETED Phase 3 445 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis

Eli Lilly and Company

NCT04178967

COMPLETED Phase 3 424 participants

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1)

Eli Lilly and Company

NCT04146363

COMPLETED 409 participants

Impact of the Severity of Pediatric Psoriasis on Childhood Body Mass Index

Northwestern University

NCT00879944

COMPLETED Phase 3 407 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults

Organon and

NCT05014568

COMPLETED Phase 3 406 participants

Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)

Organon and

NCT05032859

COMPLETED Phase 2 380 participants

Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Regeneron Pharmaceuticals

NCT01859988

COMPLETED Phase 2 321 participants

Efficacy and Safety Study of Orally Administered DS107 in Moderate to Severe Atopic Dermatitis Patients

DS Biopharma

NCT02864498

COMPLETED Phase 3 301 participants

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

LEO Pharma

NCT03526861

COMPLETED NA 300 participants

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

University of Southern California

NCT03981926

COMPLETED Phase 2 280 participants

A Study of Lebrikizumab (LY3650150) in Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT03443024

COMPLETED Phase 2 264 participants

A Phase 2 Study of CIM331 for Atopic Dermatitis Patients

Chugai Pharmaceutical

NCT01986933

COMPLETED Phase 3 241 participants

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

Incyte Corporation

NCT06238817

COMPLETED Phase 3 235 participants

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

LEO Pharma

NCT05958407

COMPLETED Phase 3 228 participants

Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.

Eli Lilly and Company

NCT04250337

COMPLETED Phase 3 221 participants

A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)

Amgen

NCT05899816

COMPLETED Phase 3 206 participants

Study to Assess the Safety and Efficacy of Lebrikizumab (LY3650150) in Adolescent Participants With Moderate-to-Severe Atopic Dermatitis

Eli Lilly and Company

NCT04250350

COMPLETED Phase 2 180 participants

Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)

Nucryst Pharmaceuticals

NCT00076375

COMPLETED Phase 2 168 participants

Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis

Vanda Pharmaceuticals

NCT02651714

COMPLETED Phase 2 151 participants

An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis

PreCision Dermatology

NCT01826461

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 48
Phase 3 28
Phase 4 19

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Atopic Dermatitis Trial Landscape

151 indexed Atopic Dermatitis studies · 55 recruiting (36%).

Phase mix: 47 late (III/IV) vs 66 early (I/II).

Top sponsor: Pfizer (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Atopic Dermatitis?

PlainTrial tracks 151 US clinical trials for Atopic Dermatitis, of which 55 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Atopic Dermatitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.