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NCT03742414 · ClinicalTrials.gov registry record · Phase 2
Seal, Stopping Eczema and Allergy Study
A Phase 2 study of Atopic Dermatitis and Eczema, sponsored by Kari Nadeau, MD, PhD.
- Active
- Registry status
- Phase 2
- Development phase
- 398
- Enrollment target
- 5
- Study locations
NCT03742414 is a Phase 2 study of Atopic Dermatitis and Eczema that is active but no longer recruiting, run by Kari Nadeau, MD, PhD. The registered enrollment target is 398 participants, below the 607-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (34% lower). The trial reports 5 study locations across 5 states.
The verdict
NCT03742414, a Phase 2 study of Atopic Dermatitis and Eczema, is active but no longer recruiting, sponsored by Kari Nadeau, MD, PhD.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 398 participants
- Enrollment target
- 5
- Study locations
Study Summary
This is a randomized, controlled trial designed for children who are have already developed atopic dermatitis (AD or eczema) by 12 weeks of age. The aim is to compare the effect of proactive sequential skin care, including the twice-daily use of a tri-lipid skin barrier cream (Epiceram) and proactive use of fluticasone propionate cream, against reactive AD therapy, to reduce the occurrence and severity of AD in early infancy and thereby prevent food allergy (FA).
Conditions Studied
Interventions
- OTHER Standard of Care
- COMBINATION_PRODUCT Tri-lipid skin barrier cream (Epiceram)
- COMBINATION_PRODUCT Fluticasone propionate Cream 0.05%
Study Locations (5)
California
- Sean N. Parker Center for Allergy & Asthma Research at Stanford University - Palo Alto
Colorado
- Division of Pediatric Allergy and Clinical Immunology, National Jewish Health - Denver
Illinois
- University of Chicago - Chicago
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
London
- • King's College London and Guy's and St. Thomas' NHS Foundation Trust, UK - London
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 398 participants |
| Start Date | 2021-06-30 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03742414
The ClinicalTrials.gov registry entry for NCT03742414 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 398 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 607-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (34% lower). The listed sponsor is Kari Nadeau, MD, PhD, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Atopic Dermatitis appearing as the primary indexed condition, and to 3 interventions - of which Standard of Care is the first listed.
NCT03742414 reports 5 study locations spanning 5 distinct geographic areas - top geographies include California, Colorado, Illinois.
Frequently Asked Questions
What is clinical trial NCT03742414 about?
NCT03742414 is a clinical study titled "Seal, Stopping Eczema and Allergy Study". This is a randomized, controlled trial designed for children who are have already developed atopic dermatitis (AD or eczema) by 12 weeks of age. The aim is to compare the effect of proactive sequential skin care, including the twice-daily use of a tri-lipid skin barrier cream (Epiceram) and proactiv...
What is the current status of trial NCT03742414?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 398 participants. The study started on 2021-06-30. Estimated completion is 2028-06-30.
What conditions does trial NCT03742414 study?
This clinical trial studies the following conditions: Atopic Dermatitis, Eczema, Atopic Dermatitis Eczema, Eczema, Infantile.
What interventions are being tested in trial NCT03742414?
The interventions under investigation include: Standard of Care (OTHER), Tri-lipid skin barrier cream (Epiceram) (COMBINATION_PRODUCT), Fluticasone propionate Cream 0.05% (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT03742414?
This trial is sponsored by Kari Nadeau, MD, PhD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03742414 being conducted?
This trial has 5 study locations across California, Colorado, Illinois, Ohio, London. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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