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NCT05651711 · ClinicalTrials.gov registry record · Phase 3
A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)
A Phase 3 study of Atopic Dermatitis, sponsored by Amgen.
- Completed
- Registry status
- Phase 3
- Development phase
- 726
- Enrollment target
- 20
- Study locations
NCT05651711 is a Phase 3 study of Atopic Dermatitis that has completed, run by Amgen. The registered enrollment target is 726 participants, above the 605-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (20% higher). The trial reports 20 study locations across 6 states.
The verdict
NCT05651711, a Phase 3 study of Atopic Dermatitis, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 726 participants
- Enrollment target
- 20
- Study locations
Study Summary
The co-primary objectives of the study are to: * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Validated Investigator's Global Assessment for Atopic Dermatitis (vIGA-AD). * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Eczema Area and Severity Index (EASI).
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Rocatinlimab
Study Locations (20)
California
- Velocity Clinical Research Chula Vista - Chula Vista
- West Coast Research LLC - Dublin
- California Dermatology and Clinical Research Institute - Encinitas
- Center for Dermatology Clinical Research Inc - Fremont
- Velocity Clinical Research - San Diego - La Mesa
- Velocity Clinical Research - North Hollywood - North Hollywood
- Cura Clinical Research - Palmdale
- University of California at San Francisco, Dermatology Clinic at Mount Zion - San Francisco
- Clinical Science Institute - Santa Monica
Florida
- Renaissance Research and Medical Group - Cape Coral
- Driven Research LLC - Coral Gables
- Saint Jude Clinical Research - Doral
- Direct Helpers Research Center - Hialeah
Arizona
- Research Solutions of Arizona, PC - Litchfield Park
- Center for Dermatology and Plastic Surgery - Scottsdale
Arkansas
- Clinical Trials Institute of Northwest Arkansas - Fayetteville
- Burke Pharmaceutical Research - Hot Springs
Colorado
- Clarity Dermatology - Castle Rock
- Velocity Clinical Research - Denver - Denver
District of Columbia
- Foxhall Research Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 726 participants |
| Start Date | 2022-12-14 |
| Est. Completion | 2024-08-27 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05651711
The ClinicalTrials.gov registry entry for NCT05651711 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 726 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 605-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (20% higher). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05651711 reports 20 study locations spanning 6 distinct geographic areas - top geographies include California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT05651711 about?
NCT05651711 is a clinical study titled "A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)". The co-primary objectives of the study are to: * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Validated Investigator's Global Assessment for Atopic Dermatitis (vIGA-AD). * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed usin...
What is the current status of trial NCT05651711?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 726 participants. The study started on 2022-12-14. Estimated completion is 2024-08-27.
What conditions does trial NCT05651711 study?
This clinical trial studies the following conditions: Atopic Dermatitis.
What interventions are being tested in trial NCT05651711?
The interventions under investigation include: Placebo (OTHER), Rocatinlimab (DRUG).
Who is sponsoring clinical trial NCT05651711?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05651711 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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