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NCT05899816 · ClinicalTrials.gov registry record · Phase 3
A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)
A Phase 3 study of Atopic Dermatitis and Moderate-to-Severe Atopic Dermatitis, sponsored by Amgen.
- Completed
- Registry status
- Phase 3
- Development phase
- 221
- Enrollment target
- 20
- Study locations
NCT05899816: Completed Phase 3 study of Atopic Dermatitis and Moderate-to-Severe Atopic Dermatitis, sponsored by Amgen.
NCT05899816 is a Phase 3 study of Atopic Dermatitis and Moderate-to-Severe Atopic Dermatitis that has completed, run by Amgen. The registered enrollment target is 221 participants, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (64% lower). The trial reports 20 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05899816, a Phase 3 study of Atopic Dermatitis and Moderate-to-Severe Atopic Dermatitis, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 221 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 24
Primary Outcome
Participants received 1 dose of a tetanus vaccine at Week 20. The antibody response to the tetanus vaccine was assessed by measuring serum anti-tetanus immunoglobulin G (IgG) by an immunoassay.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Rocatinlimab
Study Locations (20)
California
- Kern Research Inc - Bakersfield
- Hope Clinical Research LLC - Canoga Park
- Doc1 Healthcare Systems - Chino
- 310 Clinical Research - Inglewood
- Chemidox Clinical Trials Incorporated - Lancaster
- Long Beach Research Institute - Long Beach
- University of California Los Angeles - Los Angeles
- Wallace Medical Group Inc - Los Angeles
- West Los Angeles Clinical Trials - Los Angeles
- Northridge Clinical Trials - Northridge
- Havana Research Institute Inc - Pasadena
- Peninsula Research Associates - Rolling Hills Estates
- Integrative Skin Science and Research - Sacramento
- Wake Research Medical Center for Clinical Research - San Diego
- Cura Clinical Research - Sherman Oaks
Arizona
- Affiliated Dermatology - Scottsdale
- Center for Dermatology and Plastic Surgery - Scottsdale
- Scottsdale Clinical Trials - Scottsdale
- Medical Advancement Centers of Arizona - Tempe
Arkansas
- Little Rock Allergy and Asthma Clinical Research Center - Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 221 participants |
| Start Date | 2023-06-07 |
| Est. Completion | 2024-11-14 |
| Phase | Phase 3 |
What the finished NCT05899816 record still lists
NCT05899816 is an interventional study that assigns participants to a tested intervention. The registered 221 participants enrollment target is mid-sized for trials with a published cap, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05899816 names 20 study sites across 3 states, led by California, Arizona, Arkansas.
Frequently Asked Questions
What is clinical trial NCT05899816 about?
NCT05899816 is a clinical study titled "A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)". The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 2...
What is the current status of trial NCT05899816?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 221 participants. The study started on 2023-06-07. Estimated completion is 2024-11-14.
What conditions does trial NCT05899816 study?
This clinical trial studies the following conditions: Atopic Dermatitis, Moderate-to-Severe Atopic Dermatitis.
What interventions are being tested in trial NCT05899816?
The interventions under investigation include: Placebo (DRUG), Rocatinlimab (DRUG).
Who is sponsoring clinical trial NCT05899816?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05899816 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05899816's enrollment target sits among peer trials
221 52nd of 150 higher than 99 of 150 other Atopic Dermatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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