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COMPLETED Phase 3

A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)

NCT05899816 · View on ClinicalTrials.gov ↗

Study Summary

The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 24

Interventions

  • DRUG Placebo
  • DRUG Rocatinlimab

Study Locations (20)

California

  • Kern Research Inc — Bakersfield
  • Hope Clinical Research LLC — Canoga Park
  • Doc1 Healthcare Systems — Chino
  • 310 Clinical Research — Inglewood
  • Chemidox Clinical Trials Incorporated — Lancaster
  • Long Beach Research Institute — Long Beach
  • University of California Los Angeles — Los Angeles
  • Wallace Medical Group Inc — Los Angeles
  • West Los Angeles Clinical Trials — Los Angeles
  • Northridge Clinical Trials — Northridge
  • Havana Research Institute Inc — Pasadena
  • Peninsula Research Associates — Rolling Hills Estates
  • Integrative Skin Science and Research — Sacramento
  • Wake Research Medical Center for Clinical Research — San Diego
  • Cura Clinical Research — Sherman Oaks

Arizona

  • Affiliated Dermatology — Scottsdale
  • Center for Dermatology and Plastic Surgery — Scottsdale
  • Scottsdale Clinical Trials — Scottsdale
  • Medical Advancement Centers of Arizona — Tempe

Arkansas

  • Little Rock Allergy and Asthma Clinical Research Center — Little Rock

Trial Details

FieldValue
Enrollment Target 221 participants
Start Date 2023-06-07
Est. Completion 2024-11-14
Phase Phase 3

Sponsor

Amgen

266 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05899816

The ClinicalTrials.gov registry entry for NCT05899816 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 221 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05899816 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Arizona, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05899816 about?

NCT05899816 is a clinical study titled "A Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET - VOYAGER)". The primary objectives of this study are to: * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-tetanus response at Week 24 * estimate vaccine response in rocatinlimab group vs placebo group, assessed using antibody anti-meningococcal response at Week 2...

What is the current status of trial NCT05899816?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 221 participants. The study started on 2023-06-07. Estimated completion is 2024-11-14.

What conditions does trial NCT05899816 study?

This clinical trial studies the following conditions: Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05899816?

The interventions under investigation include: Placebo (DRUG), Rocatinlimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05899816?

This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05899816 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial