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ClinicalTrials.gov 55 recruiting now official registry

Atopic Dermatitis clinical trials

55 of 151 indexed Atopic Dermatitis trials are currently recruiting.

151 US clinical trials · 55 currently recruiting

Atopic Dermatitis is the subject of 151 registered US clinical trials on ClinicalTrials.gov, 55 of them currently open to new participants. 47 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is Pfizer, running 10 of these trials.

The research picture

Atopic Dermatitis has 151 registered US clinical trials, 55 of them open to new participants right now, about 36% of the total.

55
recruiting participants now
36%
of trials open to enrollment
47
in Phase 3–4 (later-stage)
10
top sponsor: Pfizer
Phase 118Phase 248Phase 328Phase 419

Active & Recent Trials

151 total, page 3 of 4

COMPLETED Phase 2 148 participants

Efficacy and Safety of MEDI3506 in Adult Subjects With Atopic Dermatitis

AstraZeneca

NCT04212169

COMPLETED Phase 2 142 participants

A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis

Bellus Health Inc. - a GSK company

NCT04693195

COMPLETED Phase 2 140 participants

A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis

Arena Pharmaceuticals

NCT04162769

COMPLETED Phase 4 137 participants

A Study of Crisaborole Ointment 2% in Children Aged 3-24 Months With Mild to Moderate Atopic Dermatitis

Pfizer

NCT03356977

COMPLETED Phase 2 104 participants

Study To Assess Efficacy, Safety, Tolerability And Pharmacokinetics Of PF-07038124 Ointment In Participants With Atopic Dermatitis Or Plaque Psoriasis

Pfizer

NCT04664153

COMPLETED Phase 1 103 participants

A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis

RAPT Therapeutics

NCT04271514

COMPLETED 100 participants

Scratch Behavior Under Standard of Care

Boston University

NCT03898427

COMPLETED Phase 1 92 participants

A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis

Otsuka Pharmaceutical Development & Commercialization

NCT01702181

COMPLETED Phase 3 92 participants

ASPIRE: PROs & Caregiver Burden in Children With Atopic Dermatitis

University of Rochester

NCT03645057

COMPLETED Phase 3 90 participants

A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color

Eli Lilly and Company

NCT05372419

COMPLETED Phase 2 87 participants

A Study to Evaluate the Safety and Efficacy of Bermekimab in Patients With Moderate to Severe Atopic Dermatitis

Janssen Research & Development

NCT04021862

COMPLETED Phase 1 82 participants

Safety, Tolerability, and Preliminary Efficacy of Soquelitinib in Participants With Moderate to Severe AD

Corvus Pharmaceuticals

NCT06345404

COMPLETED Phase 1 82 participants

Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00723489

COMPLETED NA 80 participants

Comparison of Video-Based Versus Written Patient Education on Atopic Dermatitis

University of California, Davis

NCT00826592

COMPLETED Phase 2 77 participants

A Study to Learn How Well the Study Treatment Zabedosertib (BAY1834845) Works and How Safe it is Compared to Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis

Bayer

NCT05656911

COMPLETED Phase 4 70 participants

Effects of Pimecrolimus Cream 1% on the Molecular and Cellular Profile of Adult Male Patients With Atopic Dermatitis

Novartis

NCT00117377

COMPLETED Phase 2 64 participants

To Assess the Safety and Activity of GBR 830, Compared to Placebo, in Adults With Moderate-to-severe Atopic Dermatitis

Ichnos Sciences

NCT02683928

COMPLETED NA 58 participants

Bleach Bath Treatment of Adults With Atopic Dermatitis

University of Rochester

NCT01996150

COMPLETED NA 56 participants

Clinic-Based Atopic Dermatitis Therapeutic Patient Education

Boston University

NCT04352270

COMPLETED Phase 1 54 participants

A Safety, Tolerability and Pharmacokinetics Study of Topical Ointment YR001 in Adult Healthy Volunteers

Hangzhou Yirui Pharmaceutical Technology Co.

NCT05718921

COMPLETED Phase 2 50 participants

Study of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis

Aclaris Therapeutics

NCT04598269

COMPLETED NA 45 participants

A Study Comparing the Efficacy of Two Topical Steroid Application Regimens in Pediatric Patients With Atopic Dermatitis

Yale University

NCT01675232

COMPLETED Phase 2 41 participants

Secukinumab for Treatment of Atopic Dermatitis

Icahn School of Medicine at Mount Sinai

NCT02594098

COMPLETED Phase 2 36 participants

Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis

Organon and

NCT05186805

COMPLETED Phase 4 35 participants

Epiceram Versus Elidel for Treatment of Mild to Moderate Atopic Dermatitis

Ceragenix Pharmaceuticals

NCT00460083

COMPLETED Phase 2 35 participants

Topical YR001 Ointment in Adult With Mild to Moderate Atopic Dermatitis

Hangzhou Yirui Pharmaceutical Technology Co.

NCT06309355

COMPLETED 31 participants

Molecular and Cellular Characterization of Spongiotic Dermatitis

University of California, Davis

NCT00371163

COMPLETED Phase 4 30 participants

Response of Children With Atopic Dermatitis (Eczema) to Eucrisa

Ann & Robert H Lurie Children's Hospital of Chicago

NCT04023084

COMPLETED Phase 2 30 participants

A Phase 2 Study of PH-10 for the Treatment of Atopic Dermatitis

Provectus Pharmaceuticals

NCT00690807

COMPLETED Phase 4 30 participants

Bilateral Comparison Study of Elidel 1% and Hylatopic Plus Emollient Foam for the Treatment of Subjects With Atopic Dermatitis

Frankel, Amylynne, M.D.

NCT01202149

COMPLETED 30 participants

Bone Health in Patients With Atopic Dermatitis

Mayo Clinic

NCT03800004

COMPLETED Phase 1 28 participants

A Study of B244 Delivered as a Topical Spray to Assess Safety in Pediatric Subjects With Atopic Dermatitis

AOBiome

NCT03775434

COMPLETED Phase 2 28 participants

An Open Label, Safety Study to Assess the Potential for Adrenal Suppression.

Sun Pharmaceutical Industries

NCT02932891

COMPLETED Phase 4 24 participants

Steroid-reducing Effects of Crisaborole

Johns Hopkins University

NCT03832010

COMPLETED Phase 1 24 participants

A Trial to Evaluate Pharmacokinetics, Immunogenicity, Safety, and Tolerability of LEO 138559 in Healthy Japanese Subjects

LEO Pharma

NCT05099133

COMPLETED Phase 4 24 participants

Evaluating Treatment Resistant Dermatitis TaroIIR

Wake Forest University Health Sciences

NCT03050294

COMPLETED Phase 1 22 participants

Safety, PK, PD, and Clinical Activity of Orally Administered KT-621 in Adult Patients With Atopic Dermatitis (AD)

Kymera Therapeutics

NCT06945458

COMPLETED Phase 2 22 participants

An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis

Oregon Health and Science University

NCT00806221

COMPLETED Early Phase 1 21 participants

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

Amgen

NCT05891119

COMPLETED Phase 4 20 participants

A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis

Wake Forest University Health Sciences

NCT01049243

COMPLETED 20 participants

Skin Tape Transcriptome Methods in Children

National Jewish Health

NCT04180644

COMPLETED 20 participants

Sweat and Gas Sensor for Healthy Skin and Atopic Dermatitis

Northwestern University

NCT03874039

COMPLETED Phase 4 19 participants

Study to Evaluate Effect of Pandel Cream 0.1% on HPA Axis in Pediatric and Adult Population

Fougera Pharmaceuticals

NCT01137032

COMPLETED Phase 2 19 participants

DMT210 Topical Gel in the Treatment of Atopic Dermatitis

Dermata Therapeutics

NCT02949960

COMPLETED 16 participants

Improvement of Short Term Outcome of Mild to Moderate Atopic Dermatitis Using a Combination of Crisaborole and a Concomitant Topical Corticosteroid Over a 8 Week Period

Clinical Research Center of the Carolinas

NCT04008784

COMPLETED Phase 1 12 participants

A Study to Learn How Different Forms of the Study Medicine Called PF 08049820 Are Taken up Into the Bloodstream in Healthy Adults

Pfizer

NCT07172321

COMPLETED Phase 2 10 participants

Study of Apremilast in Atopic or Contact Dermatitis

Tufts Medical Center

NCT00931242

COMPLETED NA 9 participants

Reversal of Epidermal Phenotype in Severe Atopic Dermatitis With Cyclosporine Therapy

Rockefeller University

NCT01149759

COMPLETED Phase 1 8 participants

Single Center Study Using Omalizumab in Subjects With Atopic Dermatitis

Stanford University

NCT01678092

COMPLETED Early Phase 1 7 participants

IL-4 and Insulin Resistance for Treatment of Patients With Atopic Dermatitis

Mayo Clinic

NCT05372003

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Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 48
Phase 3 28
Phase 4 19

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Atopic Dermatitis Trial Landscape

151 indexed Atopic Dermatitis studies · 55 recruiting (36%).

Phase mix: 47 late (III/IV) vs 66 early (I/II).

Top sponsor: Pfizer (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Atopic Dermatitis?

PlainTrial tracks 151 US clinical trials for Atopic Dermatitis, of which 55 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Atopic Dermatitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.