LEO Pharma

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, LEO Pharma sits in the top decile of US sponsors by registered trial count (#318 of 15,742 sponsors by registered trial count).

65 total trials 3 currently recruiting 59 completed early-phase tilt top decile by trial count

LEO Pharma: 65 sponsored US clinical trials, 3 recruiting.

LEO Pharma sponsors 65 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 59 completed. 23 of these trials are in Phase 3-4 (later-stage) and 38 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atopic Dermatitis, with 4 trials.

Top-decile sponsor footprint

LEO Pharma ranks in the top decile of sponsors by registered trial count (#318 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 78/100

59 of 62 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (95.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

65 total, page 1 of 2

RECRUITING Phase 3

A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus

NCT07335588

RECRUITING Phase 2

A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

NCT07013201

RECRUITING Phase 3

A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis

NCT06311682

COMPLETED Phase 2

A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic Dermatitis

NCT05923099

COMPLETED Phase 3

A 32-week Trial to Evaluate the Efficacy and Safety of Tralokinumab in Subjects With Moderate-to-severe Atopic Hand Eczema Who Are Candidates for Systemic Therapy

NCT05958407

COMPLETED Phase 3

The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI Ichthyosis

NCT05295732

COMPLETED Phase 2

A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing Alopecia

NCT05332366

COMPLETED Phase 3

Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA)

NCT05194540

COMPLETED Phase 1

A Trial to Evaluate Pharmacokinetics, Immunogenicity, Safety, and Tolerability of LEO 138559 in Healthy Japanese Subjects

NCT05099133

COMPLETED Phase 2

An Evaluation of LEO 138559 in Adults With Moderate to Severe Atopic Dermatitis.

NCT04922021

COMPLETED Phase 2

A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Congenital Ichthyosis

NCT04154293

TERMINATED Phase 2

Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.

NCT03958955

COMPLETED Phase 1

Delgocitinib Cream for the Treatment of Moderate to Severe Atopic Dermatitis During 8 Weeks in Adults, Adolescents, and Children

NCT03826901

COMPLETED Phase 2

Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.

NCT03725722

COMPLETED Phase 2

Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema

NCT03683719

COMPLETED Phase 1

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

NCT03556592

COMPLETED Phase 2

Vaccine Responses in Tralokinumab-Treated Atopic Dermatitis - ECZTRA 5 (ECZema TRAlokinumab Trial No. 5)

NCT03562377

COMPLETED Phase 3

Tralokinumab Monotherapy for Adolescent Subjects With Moderate to Severe Atopic Dermatitis - ECZTRA 6 (ECZema TRAlokinumab Trial no. 6).

NCT03526861

COMPLETED Phase 3

Long-term Extension Trial in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Trials - ECZTEND

NCT03587805

COMPLETED Phase 3

Tralokinumab in Combination With Topical Corticosteroids for Moderate to Severe Atopic Dermatitis - ECZTRA 3

NCT03363854

COMPLETED

A Study of Patient Concerns and Treatment Satisfaction in Patients Being Treated With Finacea Foam for Rosacea

NCT03193372

TERMINATED Phase 3

A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or Scalp

NCT03115476

COMPLETED Phase 3

Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 2 (ECZema TRAlokinumab Trial no. 2)

NCT03160885

COMPLETED Phase 3

Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 1 (ECZema TRAlokinumab Trial no. 1)

NCT03131648

COMPLETED Phase 3

LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris

NCT02899962

COMPLETED Phase 1

Biological Effects of LEO 43204 in Actinic Keratosis

NCT02600598

COMPLETED Phase 2

Explorative Trial Evaluating the Efficacy and Tolerability of LEO43204 in Moderate to Severe Acne

NCT02575950

COMPLETED Phase 2

Safety and Efficacy of Once Daily Topical Treatment With LEO 90100 Aerosol Foam in Adolescent Subjects With Plaque Psoriasis

NCT02387853

COMPLETED Phase 1

A Clinical Study to Evaluate the Sensitizing Potential of LEO 43204 Gel

NCT02650505

COMPLETED Phase 2

LEO 124249 Ointment in the Treatment of Alopecia Areata

NCT02561585

COMPLETED Phase 3

Efficacy and Safety of LEO 43204 in the Field Treatment of Actinic Keratosis on Face or Chest including12-month Follow-up

NCT02549339

COMPLETED Phase 3

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Face or Chest Including 12-month Follow-up

NCT02547233

COMPLETED Phase 3

Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up

NCT02547363

COMPLETED Phase 1

Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions

NCT02424305

COMPLETED Phase 3

Efficacy and Safety of Ingenol Mebutate Gel for Actinic Keratosis Applied on Large Area on Face, Scalp or Chest

NCT02361216

COMPLETED Phase 2

Safety of LEO 43204 for Actinic Keratosis Applied on Face/Chest, Scalp and Trunk/Extremities, Respectively

NCT02305888

COMPLETED

Preferences & Treatment Satisfaction Drivers in Rosacea Patients

NCT02602470

COMPLETED Phase 1

Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis

NCT02100813

COMPLETED Phase 1

Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis

NCT02120456

COMPLETED Phase 1

Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions

NCT02124239

COMPLETED Phase 2

An International, Multi-centre, Prospective, Non-controlled, Open, Single-group, 8-week Trial in Adolescent Subjects

NCT02038569

COMPLETED Phase 2

Efficacy and Safety of Ingenol Mebutate Gel 0.06% When Applied Once Daily for 2, 3 or 4 Consecutive Days to a Treatment Area of Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis

NCT01998984

COMPLETED Phase 1

A Study of Increasing Strengths, Safety and Efficacy of Two Formulas of LEO 43204 on the Face or the Chest in Patients With Actinic Keratosis

NCT01922050

COMPLETED

An Observational Study to Assess Patient Satisfaction and Control of Psoriasis With Calcipotriene/Betamethasone Dipropionate (Taclonex®) Topical Suspension, and Effect on Quality of Life

NCT01982552

COMPLETED Phase 3

LEO 90100 Compared to Vehicle in Subjects With Psoriasis Vulgaris

NCT01866163

COMPLETED Phase 1

Safety and Efficacy of Ingenol Mebutate Once Daily for 2 or 3 Consecutive Days in Subjects With Actinic Keratosis

NCT01820260

COMPLETED Phase 3

Safety and Efficacy of Azelaic Acid Foam, 15 % in Papulopustular Rosacea

NCT01555463

COMPLETED Phase 2

LEO 90100 Compared With Calcipotriol Plus Betamethasone Dipropionate Ointment, LEO 90100 Vehicle and Ointment Vehicle in Subjects With Psoriasis Vulgaris

NCT01536886

COMPLETED Phase 2

LEO 90100 in the Treatment of Psoriasis Vulgaris

NCT01536938

COMPLETED Phase 3

A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp

NCT01541553

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Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 24
Phase 3 22
Phase 4 1

What is open in the LEO Pharma pipeline

3 recruiting of 65 indexed (5% open); 59 completed (91%).

Phase mix: 23 late (III/IV) vs 38 early (I/II) (early-phase heavy).

Top condition: Atopic Dermatitis (4 trials), 8 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

LEO Pharma: open-pipeline peers nationwide

Peers matched on 65 registered trials and 5% open enrollment, not the therapeutic-area sidebar.

LEO Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 10203040506070 0%5%10%15%20%25% Total trials Recruiting share LEO PharmaBeiGeneGlaxo WellcomeNeurocrine BiosciencesWomen and Infants Hospital of Rhode IslandJohnson & Johnson Surgical VisionTheranicaAmphastar PharmaceuticalsCook County Health
LEO Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

LEO Pharma sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 65 trials (± recruiting share)

Sponsors near 5% open enrollment (± trial volume)

What to do with this LEO Pharma page

65 registered trials is a research-attention snapshot, not an endorsement of LEO Pharma or any single study.

  • 3 of LEO Pharma's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Atopic Dermatitis is the condition LEO Pharma studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atopic Dermatitis trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

LEO Pharma pipeline card: 65 registered trials from official public datasets.Report a data error.