Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)
NCT05032859 · View on ClinicalTrials.gov ↗
Study Summary
This is a double-blind, randomized, vehicle controlled Phase 3 study to evaluate the efficacy and safety of topical tapinarof cream, 1% compared to vehicle control cream in pediatric and adult subjects with atopic dermatitis.
Conditions Studied
Interventions
- DRUG tapinarof cream, 1%
- DRUG vehicle cream
Study Locations (20)
California
- Dermavant Investigative Site — Cerritos
- Dermavant Investigative Site — Huntington Beach
- Dermavant Investigative Site — Lancaster
- Dermavant Investigative Site — Long Beach
- Dermavant Investigative Site — Los Angeles
- Dermavant Investigative Site — San Diego
- Dermavant Investigative Site — San Francisco
- Dermavant Investigative Site — Santa Ana
- Dermavant Investigative Site — Santa Monica
Florida
- Dermavant Investigative Site — Boca Raton
- Dermavant Investigative Site — Delray Beach
- Dermavant Investigative Site — Jacksonville
- Dermavant Investigative Site — Miami
- Dermavant Investigative Site — Miami
- Dermavant Investigative Site — Miami Lakes
- Dermavant Investigative Site — Tampa
Arizona
- Dermavant Investigative Site — Scottsdale
- Dermavant Investigative Site — Scottsdale
Alabama
- Dermavant Investigative Site — Birmingham
Arkansas
- Dermavant Investigative Site — Fort Smith
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 406 participants |
| Start Date | 2021-09-23 |
| Est. Completion | 2023-02-08 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05032859
The ClinicalTrials.gov registry entry for NCT05032859 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 406 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Organon and, which has 7 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions — of which tapinarof cream, 1% is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05032859 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05032859 about?
NCT05032859 is a clinical study titled "Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)". This is a double-blind, randomized, vehicle controlled Phase 3 study to evaluate the efficacy and safety of topical tapinarof cream, 1% compared to vehicle control cream in pediatric and adult subjects with atopic dermatitis.
What is the current status of trial NCT05032859?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 406 participants. The study started on 2021-09-23. Estimated completion is 2023-02-08.
What conditions does trial NCT05032859 study?
This clinical trial studies the following conditions: Atopic Dermatitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05032859?
The interventions under investigation include: tapinarof cream, 1% (DRUG), vehicle cream (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05032859?
This trial is sponsored by Organon and, which has 7 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05032859 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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