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COMPLETED Phase 3

Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis

NCT04178967 · View on ClinicalTrials.gov ↗

Study Summary

This is a randomized, double-blind, placebo-controlled, parallel-group study which is 52 weeks in duration. The study is designed to confirm the safety and efficacy of lebrikizumab as monotherapy for treatment of moderate-to-severe atopic dermatitis utilizing a 16-week induction treatment period and a 36-week long-term maintenance treatment period.

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL Lebrikizumab

Study Locations (20)

California

  • Bakersfield Dermatology and Skin Cancer Medical Group — Bakersfield
  • Center For Dermatology Clinical Research, Inc. — Fremont
  • Woodward Centre — Fresno
  • Dermatology Research Associates — Los Angeles
  • LA Universal Research Center, INC — Los Angeles
  • University Clinical Trials, Inc. — San Diego
  • San Luis Dermatology & Laser Clinic — San Luis Obispo

Florida

  • Clinical Physiology Associates, Clinical Study Center — Fort Myers
  • Direct Helpers Medical Center — Hialeah
  • The Community Research of South Florida — Hialeah
  • Solutions Through Advanced Research, Inc. — Jacksonville

Georgia

  • Georgia Pollens Clinical Research Centers, Inc — Albany
  • Marietta Dermatology Clinical Research — Marietta
  • Advanced Medical Research — Sandy Springs

Illinois

  • Arlington Dermatology — Rolling Meadows
  • NorthShore University HealthSystem — Skokie

Arizona

  • Investigate MD — Scottsdale

Arkansas

  • Northwest Arkansas Clinical Trials Center — Rogers

Kansas

  • Kansas City Dermatology, PA — Overland Park

Louisiana

  • Meridian Clinical Research — Baton Rouge

Trial Details

FieldValue
Enrollment Target 445 participants
Start Date 2019-10-29
Est. Completion 2022-04-28
Phase Phase 3

Sponsor

Eli Lilly and Company

704 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04178967

The ClinicalTrials.gov registry entry for NCT04178967 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 445 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04178967 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04178967 about?

NCT04178967 is a clinical study titled "Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis". This is a randomized, double-blind, placebo-controlled, parallel-group study which is 52 weeks in duration. The study is designed to confirm the safety and efficacy of lebrikizumab as monotherapy for treatment of moderate-to-severe atopic dermatitis utilizing a 16-week induction treatment period and...

What is the current status of trial NCT04178967?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 445 participants. The study started on 2019-10-29. Estimated completion is 2022-04-28.

What conditions does trial NCT04178967 study?

This clinical trial studies the following conditions: Atopic Dermatitis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04178967?

The interventions under investigation include: Placebo (OTHER), Lebrikizumab (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04178967?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04178967 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial