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NCT06863961 · ClinicalTrials.gov registry record · Phase 2
A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis
A Phase 2 study of Atopic Dermatitis, sponsored by Hoffmann-La Roche.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 160
- Enrollment target
- 20
- Study locations
NCT06863961: Recruiting Phase 2 study of Atopic Dermatitis, sponsored by Hoffmann-La Roche.
NCT06863961 is a Phase 2 study of Atopic Dermatitis that is actively recruiting participants, run by Hoffmann-La Roche. The registered enrollment target is 160 participants, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06863961, a Phase 2 study of Atopic Dermatitis, is actively recruiting participants, sponsored by Hoffmann-La Roche.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 160 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to assess the efficacy and safety of Afimkibart (also known as RO7790121) in participants with moderate to severe atopic dermatitis (AD).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Afimkibart
Study Locations (20)
California
- University of California Los Angeles - Los Angeles
- Dermatology Research Associate - Los Angeles
Florida
- Suncoast Research Associates LLC - ERN - PPDS - Doral
- Olympian Clinical Research - Tampa
Georgia
- Hamilton Research, LLC - Alpharetta
- Dermatology Affiliates Research Institute, LLC - Atlanta
Indiana
- Dawes Fretzin Clinical Res LLC - Indianapolis
- Southern Indiana Clinical Trials - New Albany
New York
- Forest Hill Dermatology Group - Kew Gardens
- Weill Cornell Medicine - New York
Ohio
- Centricity Research Dublin - Dublin
- DOCS Clinical Research - Springfield - Springfield
Tennessee
- Goodlettsville Dermatology Research - Goodlettsville
- Cumberland Skin Center for Clinical Research LLC - Hermitage
Michigan
- Revival Research Institute, LLC - Troy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-04-01 |
| Est. Completion | 2027-04-19 |
| Phase | Phase 2 |
What NCT06863961 shows while recruiting
NCT06863961 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06863961 names 20 study sites across 13 states, led by California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT06863961 about?
NCT06863961 is a clinical study titled "A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis". The purpose of this study is to assess the efficacy and safety of Afimkibart (also known as RO7790121) in participants with moderate to severe atopic dermatitis (AD).
What is the current status of trial NCT06863961?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2025-04-01. Estimated completion is 2027-04-19.
What conditions does trial NCT06863961 study?
This clinical trial studies the following conditions: Atopic Dermatitis.
What interventions are being tested in trial NCT06863961?
The interventions under investigation include: Placebo (DRUG), Afimkibart (DRUG).
Who is sponsoring clinical trial NCT06863961?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06863961 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Atopic Dermatitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06863961's enrollment target sits among peer trials
160 68th of 150 higher than 82 of 150 other Atopic Dermatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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