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NCT06627335 · ClinicalTrials.gov registry record
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis
A clinical trial of Atopic Dermatitis and Pregnancy Related, sponsored by Incyte Corporation.
- Recruiting
- Registry status
- 5,621
- Enrollment target
- 1
- Study location
NCT06627335: Recruiting study of Atopic Dermatitis and Pregnancy Related, sponsored by Incyte Corporation.
NCT06627335 is a study of Atopic Dermatitis and Pregnancy Related that is actively recruiting participants, run by Incyte Corporation. The registered enrollment target is 5,621 participants, above the 572-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (883% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06627335, a study of Atopic Dermatitis and Pregnancy Related, is actively recruiting participants, sponsored by Incyte Corporation.
- RECRUITING
- Registry status
- 5,621 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is to assess infant outcomes of women with AD who were exposed to ruxolitinib cream during pregnancy compared with a control cohort of women with AD who were exposed to a topical corticosteroid (TCS) during pregnancy.
Primary Outcome
Defined as any major structural or chromosomal defect in live-born infants, stillbirths or spontaneous losses equal to or greater than 20 weeks' gestation, or electively terminated pregnancies of any gestational age.
Conditions Studied
Interventions
- DRUG Ruxolitinib Cream
- DRUG TCS
Study Locations (1)
North Carolina
- Syneos Health (remote site) - Morrisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5,621 participants |
| Start Date | 2023-03-27 |
| Est. Completion | 2028-08-15 |
What NCT06627335 shows while recruiting
NCT06627335 is an observational study that tracks outcomes without assigning an intervention. Its 5,621 participants enrollment target places it among the larger protocols in the corpus, above the 572-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (883% higher).
The record links to 2 conditions, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Ruxolitinib Cream is the first listed.
NCT06627335 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06627335 about?
NCT06627335 is a clinical study titled "An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis Exposed to Ruxolitinib Cream Versus Topical Corticosteroids During Pregnancy: A US Claims Database Analysis". This study is to assess infant outcomes of women with AD who were exposed to ruxolitinib cream during pregnancy compared with a control cohort of women with AD who were exposed to a topical corticosteroid (TCS) during pregnancy.
What is the current status of trial NCT06627335?
This trial is currently recruiting. The enrollment target is 5,621 participants. The study started on 2023-03-27. Estimated completion is 2028-08-15.
What conditions does trial NCT06627335 study?
This clinical trial studies the following conditions: Atopic Dermatitis, Pregnancy Related.
What interventions are being tested in trial NCT06627335?
The interventions under investigation include: Ruxolitinib Cream (DRUG), TCS (DRUG).
Who is sponsoring clinical trial NCT06627335?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06627335 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Atopic Dermatitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06627335's enrollment target sits among peer trials
5,621 4th of 150 higher than 147 of 150 other Atopic Dermatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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