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NCT06808477 · ClinicalTrials.gov registry record · Phase 1

A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)

A Phase 1 study of Atopic Dermatitis, sponsored by Bambusa Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
198
Enrollment target
7
Study locations

NCT06808477: Recruiting Phase 1 study of Atopic Dermatitis, sponsored by Bambusa Therapeutics.

NCT06808477 is a Phase 1 study of Atopic Dermatitis that is actively recruiting participants, run by Bambusa Therapeutics. The registered enrollment target is 198 participants, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (67% lower). The trial reports 7 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06808477, a Phase 1 study of Atopic Dermatitis, is actively recruiting participants, sponsored by Bambusa Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
198 participants
Enrollment target
7
Study locations

Study Summary

This is a Phase 1, randomized, blinded, placebo controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis (AD).

Primary Outcome

Incidence, relatedness, and severity of adverse events graded per NCI CTCAE v5.0.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG BBT001

Study Locations (7)

Auckland

  • Optimal Clinical Trials Central Auckland - Grafton
  • Aotearoa Clinical Trials - Otahuhu
  • Pacific Clinical Research Network (PCRN) - Auckland - Takapuna

New York

  • Equity Medical, LLC - The Bronx

Western Australia

  • Linear Clinical Research - Perth

Christchurch

  • Optimal Clinical Trials Ltd - Christchurch - Christchurch Central City

Other

  • Pacific Clinical Research Network (PCRN) Wellington - Upper Hutt

Trial Details

FieldValue
Enrollment Target 198 participants
Start Date 2025-02-27
Est. Completion 2027-02-06
Phase Phase 1
Bambusa Therapeutics

2 total trials

What NCT06808477 shows while recruiting

NCT06808477 is an interventional study that assigns participants to a tested intervention. The registered 198 participants enrollment target is mid-sized for trials with a published cap, below the 608-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (67% lower).

The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06808477 lists 7 locations in 5 states (Auckland, New York, Western Australia).

Frequently Asked Questions

What is clinical trial NCT06808477 about?

NCT06808477 is a clinical study titled "A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)". This is a Phase 1, randomized, blinded, placebo controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study of BBT001 in healthy volunteers (HVs) and adult patients with moderate to severe Atopic Dermatitis (AD).

What is the current status of trial NCT06808477?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 198 participants. The study started on 2025-02-27. Estimated completion is 2027-02-06.

What conditions does trial NCT06808477 study?

This clinical trial studies the following conditions: Atopic Dermatitis.

What interventions are being tested in trial NCT06808477?

The interventions under investigation include: Placebo (DRUG), BBT001 (DRUG).

Who is sponsoring clinical trial NCT06808477?

This trial is sponsored by Bambusa Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06808477 being conducted?

This trial has 7 study locations across New York, Western Australia, Auckland, Christchurch. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Atopic Dermatitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06808477's enrollment target sits among peer trials

198 63rd of 150 higher than 88 of 150 other Atopic Dermatitis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06808477, the US trial registry maintained by the National Library of Medicine. NCT06808477 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.