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COMPLETED Phase 3

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)

NCT02892149 · View on ClinicalTrials.gov ↗

Study Summary

A multicenter, randomized, open-label, active-controlled Phase 3 study for the maintenance treatment of anemia in participants with dialysis-dependent chronic kidney disease (DD-CKD)

Interventions

  • DRUG Vadadustat
  • DRUG Darbepoetin alfa

Study Locations (20)

California

  • Research Site — Anaheim
  • Research Site #1 — Bakersfield
  • Research Site #2 — Bakersfield
  • Research Site — Canyon Country
  • Research Site — Chula Vista
  • Research Site — Downey
  • Research Site — El Centro
  • Research Site — Escondido
  • Research Site — Fairfield
  • Research Site — Glendale
  • Research Site #1 — Granada Hills
  • Research Site #2 — Granada Hills
  • Research Site — La Habra
  • Research Site — La Mesa
  • Research Site — Lakewood
  • Research Site — Long Beach
  • Research Site — Long Beach

Alabama

  • Research Site — Huntsville

Arizona

  • Research Site — Mesa

Arkansas

  • Research Site — Pine Bluff

Trial Details

FieldValue
Enrollment Target 3,554 participants
Start Date 2016-08
Est. Completion 2020-03-30
Phase Phase 3

Sponsor

Akebia Therapeutics

9 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02892149

The ClinicalTrials.gov registry entry for NCT02892149 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,554 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Akebia Therapeutics, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Anemia appearing as the primary indexed condition, and to 2 interventions — of which Vadadustat is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02892149 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Alabama, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02892149 about?

NCT02892149 is a clinical study titled "Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)". A multicenter, randomized, open-label, active-controlled Phase 3 study for the maintenance treatment of anemia in participants with dialysis-dependent chronic kidney disease (DD-CKD)

What is the current status of trial NCT02892149?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,554 participants. The study started on 2016-08. Estimated completion is 2020-03-30.

What conditions does trial NCT02892149 study?

This clinical trial studies the following conditions: Anemia, Dialysis-Dependent Chronic Kidney Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02892149?

The interventions under investigation include: Vadadustat (DRUG), Darbepoetin alfa (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02892149?

This trial is sponsored by Akebia Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02892149 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial