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NCT05732961 · ClinicalTrials.gov registry record · Phase 2
Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms
A Phase 2 study of Myelodysplastic Syndromes and Anemia, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT05732961: Recruiting Phase 2 study of Myelodysplastic Syndromes and Anemia, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
NCT05732961 is a Phase 2 study of Myelodysplastic Syndromes and Anemia that is actively recruiting participants, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 70 participants, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05732961, a Phase 2 study of Myelodysplastic Syndromes and Anemia, is actively recruiting participants, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to see if participants with anemia due to their type of MDS or MDS/MPN will experience a more decreased need for regular blood transfusions if they take luspatercept plus best supportive care, and what effect, good and/or bad, luspatercept has on them and their anemia due to MDS or MDS/MPN. The safety and tolerability of luspatercept will also be evaluated in this study.
Primary Outcome
RBC transfusion independence (RBC-TI) as defined by IWG 2006 MDS response criteria
Conditions Studied
Interventions
- DRUG Luspatercept
Study Locations (1)
Florida
- Moffitt Cancer Center - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-02-21 |
| Est. Completion | 2026-09 |
| Phase | Phase 2 |
What NCT05732961 shows while recruiting
NCT05732961 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (75% lower).
The record links to 3 conditions, with Myelodysplastic Syndromes appearing as the primary indexed condition, and to 1 intervention - of which Luspatercept is the first listed.
NCT05732961 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05732961 about?
NCT05732961 is a clinical study titled "Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms". The purpose of the study is to see if participants with anemia due to their type of MDS or MDS/MPN will experience a more decreased need for regular blood transfusions if they take luspatercept plus best supportive care, and what effect, good and/or bad, luspatercept has on them and their anemia due...
What is the current status of trial NCT05732961?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2023-02-21. Estimated completion is 2026-09.
What conditions does trial NCT05732961 study?
This clinical trial studies the following conditions: Myelodysplastic Syndromes, Anemia, Myeloproliferative Neoplasm.
What interventions are being tested in trial NCT05732961?
The interventions under investigation include: Luspatercept (DRUG).
Who is sponsoring clinical trial NCT05732961?
This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05732961 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Myelodysplastic Syndromes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05732961's enrollment target sits among peer trials
70 74th of 173 higher than 100 of 173 other Myelodysplastic Syndromes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myelodysplastic Syndromes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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