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NCT01702805 · ClinicalTrials.gov registry record · NA
Transfusion of Prematures Trial
A NA study of Anemia and Infant, Small for Gestational Age, sponsored by NICHD Neonatal Research Network.
- Completed
- Registry status
- NA
- Development phase
- 1,824
- Enrollment target
- 20
- Study locations
NCT01702805: Completed NA study of Anemia and Infant, Small for Gestational Age, sponsored by NICHD Neonatal Research Network.
NCT01702805 is a NA study of Anemia and Infant, Small for Gestational Age that has completed, run by NICHD Neonatal Research Network. The registered enrollment target is 1,824 participants, above the 402-participant average among 72 other Anemia trials with a reported enrollment target (354% higher). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01702805, a NA study of Anemia and Infant, Small for Gestational Age, has completed, sponsored by NICHD Neonatal Research Network.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,824 participants
- Enrollment target
- 20
- Study locations
Study Summary
The objective of the TOP trial is to determine whether higher hemoglobin thresholds for transfusing ELBW infants resulting in higher hemoglobin levels lead to improvement in the primary outcome of survival and rates of neurodevelopmental impairment (NDI) at 22-26 months of age, using standardized assessments by Bayley.
Primary Outcome
A composite outcome that measures the occurrence of death or neurodevelomental impairment between birth and 22-26 months corrected age.
Conditions Studied
Interventions
- PROCEDURE Liberal Cell Transfusion
- PROCEDURE Restricted red cell transfusion
Study Locations (20)
Ohio
- Cincinnati Children's Medical Center - Cincinnati
- Case Western Reserve University, Rainbow Babies and Children's Hospital - Cleveland
- Research Institute at Nationwide Children's Hospital - Columbus
California
- University of California - Los Angeles - Los Angeles
- Stanford University - Palo Alto
North Carolina
- RTI International - Durham
- Duke University - Durham
Texas
- University of Texas Southwestern Medical Center at Dallas - Dallas
- University of Texas Health Science Center at Houston - Houston
Alabama
- University of Alabama at Birmingham - Birmingham
Georgia
- Emory University - Atlanta
Indiana
- Indiana University - Indianapolis
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,824 participants |
| Start Date | 2012-12 |
| Est. Completion | 2025-04-29 |
| Phase | NA |
What the finished NCT01702805 record still lists
NCT01702805 is an interventional study that assigns participants to a tested intervention. Its 1,824 participants enrollment target places it among the larger protocols in the corpus, above the 402-participant average among 72 other Anemia trials with a reported enrollment target (354% higher).
The record links to 5 conditions, with Anemia appearing as the primary indexed condition, and to 2 interventions - of which Liberal Cell Transfusion is the first listed.
NCT01702805 names 20 study sites across 15 states, led by Ohio, California, North Carolina.
Frequently Asked Questions
What is clinical trial NCT01702805 about?
NCT01702805 is a clinical study titled "Transfusion of Prematures Trial". The objective of the TOP trial is to determine whether higher hemoglobin thresholds for transfusing ELBW infants resulting in higher hemoglobin levels lead to improvement in the primary outcome of survival and rates of neurodevelopmental impairment (NDI) at 22-26 months of age, using standardized as...
What is the current status of trial NCT01702805?
This trial is currently completed. It is a NA study. The enrollment target is 1,824 participants. The study started on 2012-12. Estimated completion is 2025-04-29.
What conditions does trial NCT01702805 study?
This clinical trial studies the following conditions: Anemia, Infant, Small for Gestational Age, Infant, Newborn, Diseases, Bronchopulmonary Dysplasia (BPD), Infant, Extremely Low Birth Weight.
What interventions are being tested in trial NCT01702805?
The interventions under investigation include: Liberal Cell Transfusion (PROCEDURE), Restricted red cell transfusion (PROCEDURE).
Who is sponsoring clinical trial NCT01702805?
This trial is sponsored by NICHD Neonatal Research Network, which has 61 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01702805 being conducted?
This trial has 20 study locations across Alabama, California, Georgia, Indiana, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01702805's enrollment target sits among peer trials
1,824 5th of 72 higher than 68 of 72 other Anemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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