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ACTIVE NOT RECRUITING Phase 3

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

NCT00843882 · View on ClinicalTrials.gov ↗

Study Summary

This randomized phase III trial studies lenalidomide to see how well it works with or without epoetin alfa in treating patients with myelodysplastic syndrome and anemia. Lenalidomide may stop the growth of myelodysplastic syndrome by blocking blood flow to the cells. Colony stimulating factors, such as epoetin alfa, may increase the number of immune cells found in bone marrow or peripheral blood. It is not yet known whether lenalidomide is more effective with or without epoetin alfa in treating patients with myelodysplastic syndrome and anemia.

Interventions

  • PROCEDURE Bone Marrow Biopsy
  • OTHER Laboratory Biomarker Analysis
  • DRUG Lenalidomide
  • BIOLOGICAL Epoetin Alfa

Study Locations (20)

California

  • Kaiser Permanente-Anaheim — Anaheim
  • Kaiser Permanente-Baldwin Park — Baldwin Park
  • Kaiser Permanente-Bellflower — Bellflower
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank
  • Kaiser Permanente-Fontana — Fontana
  • Marin Cancer Care Inc — Greenbrae
  • Kaiser Permanente South Bay — Harbor City
  • Kaiser Permanente-Irvine — Irvine
  • Kaiser Permanente Los Angeles Medical Center — Los Angeles
  • Kaiser Permanente West Los Angeles — Los Angeles

Alaska

  • Alaska Breast Care and Surgery LLC — Anchorage
  • Alaska Women's Cancer Care — Anchorage
  • Anchorage Oncology Centre — Anchorage
  • Katmai Oncology Group — Anchorage
  • Providence Alaska Medical Center — Anchorage
  • Fairbanks Memorial Hospital — Fairbanks

Arizona

  • Mayo Clinic in Arizona — Scottsdale
  • Banner University Medical Center - Tucson — Tucson
  • University of Arizona Cancer Center-North Campus — Tucson

Alabama

  • University of Alabama at Birmingham Cancer Center — Birmingham

Trial Details

FieldValue
Enrollment Target 247 participants
Start Date 2009-01-29
Est. Completion 2026-10-02
Phase Phase 3

Sponsor

National Cancer Institute (NCI)

2,390 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00843882

The ClinicalTrials.gov registry entry for NCT00843882 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 247 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 2,390 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Myelodysplastic Syndrome appearing as the primary indexed condition, and to 4 interventions — of which Bone Marrow Biopsy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00843882 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Alaska, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00843882 about?

NCT00843882 is a clinical study titled "Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia". This randomized phase III trial studies lenalidomide to see how well it works with or without epoetin alfa in treating patients with myelodysplastic syndrome and anemia. Lenalidomide may stop the growth of myelodysplastic syndrome by blocking blood flow to the cells. Colony stimulating factors, such...

What is the current status of trial NCT00843882?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 247 participants. The study started on 2009-01-29. Estimated completion is 2026-10-02.

What conditions does trial NCT00843882 study?

This clinical trial studies the following conditions: Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Anemia, De Novo Myelodysplastic Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00843882?

The interventions under investigation include: Bone Marrow Biopsy (PROCEDURE), Laboratory Biomarker Analysis (OTHER), Lenalidomide (DRUG), Epoetin Alfa (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00843882?

This trial is sponsored by National Cancer Institute (NCI), which has 2,390 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00843882 being conducted?

This trial has 20 study locations across Alabama, Alaska, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial