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NCT02251912 · ClinicalTrials.gov registry record · Phase 2

Oxytocin Treatment of Alcohol Dependence

A Phase 2 study of Alcohol Dependence, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
Phase 2
Development phase
22
Enrollment target
1
Study location

NCT02251912 is a Phase 2 study of Alcohol Dependence that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 22 participants, below the 313-participant average among 43 other Alcohol Dependence trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02251912, a Phase 2 study of Alcohol Dependence, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
Phase 2
Development phase
22 participants
Enrollment target
1
Study location

Study Summary

Purpose: Test whether oxytocin treatment decreases drinking in people who have been consuming alcohol heavily for long periods and are physically and psychologically dependent on alcohol. Participants: 50 adults with alcohol dependence Procedures (methods): Oxytocin or placebo will be administered three times a day for the first 2 days followed by twice daily intranasal doses for the rest of the 12 weeks. Before, during and at the end of the trial, each subject will undergo evaluations including breathalyzer readings, rating withdrawal symptoms, interviews about amount of alcohol consumed since last clinic visit, subject self-ratings of anxiety, alcohol craving and, at some visits, laboratory measures (blood and urine) to monitor safety and alcohol/drug use. Following the active phase of the trial, subjects will be followed up at 4 weeks and 12 weeks to evaluate for post-medication safety and efficacy

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Intranasal Oxytocin

Study Locations (1)

North Carolina

  • University of North Carolina at Chapel Hill - Chapel Hill

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2015-07
Est. Completion 2016-09
Phase Phase 2

What the Registry Record Tells You About NCT02251912

The ClinicalTrials.gov registry entry for NCT02251912 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 313-participant average among 43 other Alcohol Dependence trials with a reported enrollment target (93% lower). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcohol Dependence appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02251912 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT02251912 about?

NCT02251912 is a clinical study titled "Oxytocin Treatment of Alcohol Dependence". Purpose: Test whether oxytocin treatment decreases drinking in people who have been consuming alcohol heavily for long periods and are physically and psychologically dependent on alcohol. Participants: 50 adults with alcohol dependence Procedures (methods): Oxytocin or placebo will be administered...

What is the current status of trial NCT02251912?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2015-07. Estimated completion is 2016-09.

What conditions does trial NCT02251912 study?

This clinical trial studies the following conditions: Alcohol Dependence.

What interventions are being tested in trial NCT02251912?

The interventions under investigation include: Placebo (DRUG), Intranasal Oxytocin (DRUG).

Who is sponsoring clinical trial NCT02251912?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02251912 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.