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NCT06684483 · ClinicalTrials.gov registry record
The Impact of Heavy Alcohol Use on Saliva and Oral Health
A clinical trial of Alcohol Use Disorder and Alcohol Dependence, sponsored by National Institutes of Health Clinical Center (CC).
- Recruiting
- Registry status
- 72
- Enrollment target
- 1
- Study location
NCT06684483: Recruiting study of Alcohol Use Disorder and Alcohol Dependence, sponsored by National Institutes of Health Clinical Center (CC).
NCT06684483 is a study of Alcohol Use Disorder and Alcohol Dependence that is actively recruiting participants, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 72 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06684483, a study of Alcohol Use Disorder and Alcohol Dependence, is actively recruiting participants, sponsored by National Institutes of Health Clinical Center (CC).
- RECRUITING
- Registry status
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke. Researchers want to learn more about how to identify developing inflammation in the mouth. They also want to know how improved oral health education and behaviors can affect inflammation in people with AUD. Objective: This study has 2 goals: (1) to test the usefulness of a new questionnaire about oral health and (2) to learn more about how oral health behaviors affect inflammation in people with AUD. Eligibility: People aged 18 years and older who are staying on an inpatient unit being treated for AUD. Healthy volunteers are also needed. Design: The study is divided into 2 parts: People will participate in either one part or the other. In part 1, participants will have 1 visit. They will have a physical exam. They will answer 18 questions for a survey about how they care for their teeth. In part 2, participants with AUD will have a physical exam. They will provide saliva and blood samples. They will have a dental exam with X-rays. They will fill out questionnaires about their health, mental health, social habits, diet, and sleep. They will keep a diary of their nicotine use for 4 weeks while inpatient. Healthy volunteers will have 1 visit. They will have a physical exam and provide blood and saliva samples. They will have a dental exam with X-rays. They will fill out questionnaires.
Primary Outcome
The endpoint will refine the OHBA questionnaire, if needed, to improve subject understanding and acceptability of the questions in the instrument; a primary measure in the Part 2 portion of the current study.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2025-01-09 |
| Est. Completion | 2026-12-31 |
What NCT06684483 shows while recruiting
NCT06684483 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (78% lower).
The record links to 2 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 0 interventions.
NCT06684483 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06684483 about?
NCT06684483 is a clinical study titled "The Impact of Heavy Alcohol Use on Saliva and Oral Health". Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke. Researchers want to learn more about how to identify developing inflammation in the mouth. They also want to know h...
What is the current status of trial NCT06684483?
This trial is currently recruiting. The enrollment target is 72 participants. The study started on 2025-01-09. Estimated completion is 2026-12-31.
What conditions does trial NCT06684483 study?
This clinical trial studies the following conditions: Alcohol Use Disorder, Alcohol Dependence.
Who is sponsoring clinical trial NCT06684483?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06684483 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06684483's enrollment target sits among peer trials
72 109th of 184 higher than 76 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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