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NCT06684483 · ClinicalTrials.gov registry record

The Impact of Heavy Alcohol Use on Saliva and Oral Health

A clinical trial of Alcohol Use Disorder and Alcohol Dependence, sponsored by National Institutes of Health Clinical Center (CC).

Recruiting
Registry status
72
Enrollment target
1
Study location

NCT06684483 is a study of Alcohol Use Disorder and Alcohol Dependence that is actively recruiting participants, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 72 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06684483, a study of Alcohol Use Disorder and Alcohol Dependence, is actively recruiting participants, sponsored by National Institutes of Health Clinical Center (CC).

RECRUITING
Registry status
72 participants
Enrollment target
1
Study location

Study Summary

Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke. Researchers want to learn more about how to identify developing inflammation in the mouth. They also want to know how improved oral health education and behaviors can affect inflammation in people with AUD. Objective: This study has 2 goals: (1) to test the usefulness of a new questionnaire about oral health and (2) to learn more about how oral health behaviors affect inflammation in people with AUD. Eligibility: People aged 18 years and older who are staying on an inpatient unit being treated for AUD. Healthy volunteers are also needed. Design: The study is divided into 2 parts: People will participate in either one part or the other. In part 1, participants will have 1 visit. They will have a physical exam. They will answer 18 questions for a survey about how they care for their teeth. In part 2, participants with AUD will have a physical exam. They will provide saliva and blood samples. They will have a dental exam with X-rays. They will fill out questionnaires about their health, mental health, social habits, diet, and sleep. They will keep a diary of their nicotine use for 4 weeks while inpatient. Healthy volunteers will have 1 visit. They will have a physical exam and provide blood and saliva samples. They will have a dental exam with X-rays. They will fill out questionnaires.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2025-01-09
Est. Completion 2026-12-31

What the Registry Record Tells You About NCT06684483

The ClinicalTrials.gov registry entry for NCT06684483 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (78% lower). The listed sponsor is National Institutes of Health Clinical Center (CC), which has 338 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 0 interventions.

NCT06684483 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT06684483 about?

NCT06684483 is a clinical study titled "The Impact of Heavy Alcohol Use on Saliva and Oral Health". Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke. Researchers want to learn more about how to identify developing inflammation in the mouth. They also want to know h...

What is the current status of trial NCT06684483?

This trial is currently recruiting. The enrollment target is 72 participants. The study started on 2025-01-09. Estimated completion is 2026-12-31.

What conditions does trial NCT06684483 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Alcohol Dependence.

Who is sponsoring clinical trial NCT06684483?

This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06684483 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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