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NCT01657760 · ClinicalTrials.gov registry record · Phase 1
Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
A Phase 1 study of Alcohol Dependence, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- Phase 1
- Development phase
- 31
- Enrollment target
- 1
- Study location
NCT01657760 is a Phase 1 study of Alcohol Dependence that has completed, run by VA Office of Research and Development. The registered enrollment target is 31 participants, below the 313-participant average among 43 other Alcohol Dependence trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01657760, a Phase 1 study of Alcohol Dependence, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 31 participants
- Enrollment target
- 1
- Study location
Study Summary
Alcohol use disorders (AUDs) are highly prevalent among U.S. civilians, and even more prevalent in the U.S. Veteran population. AUDs are frequently co-morbid with depressive symptoms in psychiatric clinical populations, resulting in an increased severity of both conditions. Indeed, returning Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans have extraordinarily high rates of alcohol misuse and co-morbid psychiatric symptoms, indicating that future Veteran clinical populations will be particularly affected by AUDs. While FDA-approved medications are available to treat AUDs, their efficacy is low compared to available psychosocial treatments. Despite the lack of evidence for efficacy from controlled trials, antidepressants are frequently prescribed to clinical populations (including Veterans) with active AUDs. A better understanding of patient-level clinical variables that may confer poor response to treatment with antidepressants would allow clinicians better tools to distinguish those alcohol-dependent Veterans likely to do worse with antidepressant treatment.
Conditions Studied
Interventions
- DRUG citalopram
Study Locations (1)
California
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA - West Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2014-05-01 |
| Est. Completion | 2017-09-01 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01657760
The ClinicalTrials.gov registry entry for NCT01657760 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 313-participant average among 43 other Alcohol Dependence trials with a reported enrollment target (90% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Alcohol Dependence appearing as the primary indexed condition, and to 1 intervention - of which citalopram is the first listed.
NCT01657760 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT01657760 about?
NCT01657760 is a clinical study titled "Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics". Alcohol use disorders (AUDs) are highly prevalent among U.S. civilians, and even more prevalent in the U.S. Veteran population. AUDs are frequently co-morbid with depressive symptoms in psychiatric clinical populations, resulting in an increased severity of both conditions. Indeed, returning Operati...
What is the current status of trial NCT01657760?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2014-05-01. Estimated completion is 2017-09-01.
What conditions does trial NCT01657760 study?
This clinical trial studies the following conditions: Alcohol Dependence.
What interventions are being tested in trial NCT01657760?
The interventions under investigation include: citalopram (DRUG).
Who is sponsoring clinical trial NCT01657760?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01657760 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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