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NCT00639288 · ClinicalTrials.gov registry record · Phase 2
Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence
A Phase 2 study of PTSD and Alcohol Dependence, sponsored by Yale University.
- Completed
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT00639288: Completed Phase 2 study of PTSD and Alcohol Dependence, sponsored by Yale University.
NCT00639288 is a Phase 2 study of PTSD and Alcohol Dependence that has completed, run by Yale University. The registered enrollment target is 9 participants, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00639288, a Phase 2 study of PTSD and Alcohol Dependence, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
Objective: To develop a detailed treatment manual that modifies the existing CPT-C treatment protocol to allow for concurrent treatment of PTSD and AD, and to obtain some pilot data regarding its efficacy. Hypothesis: We predict that CPT-C will significantly reduce the number of drinking days (measured by the Timeline Follow Back Method \[TLFB\]) and reduce the symptoms of PTSD (measured by the \[CAPS and PCL\] scores). Design: This is a non-randomized, prospective study in which all participants will receive the modified CPT-C for 12 weeks by trained CPT-C clinicians, with each session lasting approximately 1-1.5 hours). Modifications to CPT-C include psychoeducation about alcohol use as an avoidance of PTSD symptoms integrated throughout treatment, integration of coping skills training for AD, weekly breathalyzer tests to measure blood alcohol level, and use and collection of daily dairies of alcohol use.
Conditions Studied
Interventions
- OTHER modified CPT-C
Study Locations (1)
Connecticut
- VA Connecticut Healthcare System - West Haven Campus - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2008-03 |
| Est. Completion | 2015-04 |
| Phase | Phase 2 |
What the finished NCT00639288 record still lists
NCT00639288 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with PTSD appearing as the primary indexed condition, and to 1 intervention - of which modified CPT-C is the first listed.
NCT00639288 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT00639288 about?
NCT00639288 is a clinical study titled "Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence". Objective: To develop a detailed treatment manual that modifies the existing CPT-C treatment protocol to allow for concurrent treatment of PTSD and AD, and to obtain some pilot data regarding its efficacy. Hypothesis: We predict that CPT-C will significantly reduce the number of drinking days (meas...
What is the current status of trial NCT00639288?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2008-03. Estimated completion is 2015-04.
What conditions does trial NCT00639288 study?
This clinical trial studies the following conditions: PTSD, Alcohol Dependence.
What interventions are being tested in trial NCT00639288?
The interventions under investigation include: modified CPT-C (OTHER).
Who is sponsoring clinical trial NCT00639288?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00639288 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for PTSD
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00639288's enrollment target sits among peer trials
9 153rd of 154 higher than 2 of 154 other PTSD trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PTSD trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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