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NCT02178644 · ClinicalTrials.gov registry record · Phase 1
Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer
A Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT02178644: Completed Phase 1 study, sponsored by Yale University.
NCT02178644 is a Phase 1 study that has completed, run by Yale University. The registered enrollment target is 29 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02178644, a Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
This pilot study focuses on KD018 and will investigate the effect of this agent on reducing the Gastrointestinal (GI) toxicity associated with combined modality therapy of locally-advanced rectal cancer.
Primary Outcome
Grade 3-4 toxicity rate will be described as greatest toxicity per patient/total patients evaluable for toxicity +/- 95% confidence interval.
Interventions
- DRUG Chemo with concomitant Capecitabine and KD018
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2014-07 |
| Est. Completion | 2019-09-20 |
| Phase | Phase 1 |
What the finished NCT02178644 record still lists
NCT02178644 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 1 intervention - of which Chemo with concomitant Capecitabine and KD018 is the first listed.
NCT02178644 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02178644 about?
NCT02178644 is a clinical study titled "Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer". This pilot study focuses on KD018 and will investigate the effect of this agent on reducing the Gastrointestinal (GI) toxicity associated with combined modality therapy of locally-advanced rectal cancer.
What is the current status of trial NCT02178644?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2014-07. Estimated completion is 2019-09-20.
What interventions are being tested in trial NCT02178644?
The interventions under investigation include: Chemo with concomitant Capecitabine and KD018 (DRUG).
Who is sponsoring clinical trial NCT02178644?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02178644's enrollment target sits among peer trials
29 1440th of 2000 higher than 554 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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