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NCT02282878 · ClinicalTrials.gov registry record · NA
The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis
A NA study, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
NCT02282878: Completed NA study, sponsored by Yale University.
NCT02282878 is a NA study that has completed, run by Yale University. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02282878, a NA study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
Study Summary
The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls. This study primarily tests the hypothesis that higher dietary salt intake will be associated with a higher frequency of pathogenic Th17 cells and impaired function of protective regulatory T cells. If a relationship between dietary salt intake and immune function is observed, this study will also test: a) whether this relationship is unique to MS subjects or whether it is also present in healthy controls, and b) whether healthier immune function can be restored by restricting dietary salt intake.
Primary Outcome
Frequency of Th17 cells will be measured by flow cytometry through blood samples taken before and after each of the two week low sodium and high sodium diets
Interventions
- DIETARY_SUPPLEMENT High/Low Sodium Diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2014-09 |
| Est. Completion | 2019-12-08 |
| Phase | NA |
What the finished NCT02282878 record still lists
NCT02282878 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which High/Low Sodium Diet is the first listed.
NCT02282878 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02282878 about?
NCT02282878 is a clinical study titled "The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis". The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls. This study primarily tests the hypothesis that higher dietary salt intake will be associated with a higher frequency of pathogenic Th17 cells a...
What is the current status of trial NCT02282878?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2014-09. Estimated completion is 2019-12-08.
What interventions are being tested in trial NCT02282878?
The interventions under investigation include: High/Low Sodium Diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02282878?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02282878's enrollment target sits among peer trials
14 1909th of 2000 higher than 90 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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