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NCT02094872 · ClinicalTrials.gov registry record · Phase 2

Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic

A Phase 2 study, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
49
Enrollment target

NCT02094872: Completed Phase 2 study, sponsored by Yale University.

NCT02094872 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 49 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02094872, a Phase 2 study, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
49 participants
Enrollment target

Study Summary

This phase II trial studies how well molecularly targeted therapy works in treating patients with melanoma that has spread to other parts of the body. Patients must have received or do not qualify for prior immunotherapy. Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific types of cancer cells with less harm to normal cells. Molecularly targeted therapy works by treating patients with substances that kill cancer cells by targeting key molecules involved in cancer cell growth.

Primary Outcome

The best overall response rate (BORR) was assessed up to 1 year.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER cytology specimen collection procedure
  • OTHER quality-of-life assessment
  • PROCEDURE therapeutic procedure
  • DRUG MEK 162 therapy or molecularly targeted therapy

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2014-05
Est. Completion 2018-12
Phase Phase 2
Yale University

1,492 total trials

What the finished NCT02094872 record still lists

NCT02094872 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% lower).

The record links to 0 conditions, and to 5 interventions - of which laboratory biomarker analysis is the first listed.

NCT02094872 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02094872 about?

NCT02094872 is a clinical study titled "Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic". This phase II trial studies how well molecularly targeted therapy works in treating patients with melanoma that has spread to other parts of the body. Patients must have received or do not qualify for prior immunotherapy. Targeted therapy is a type of treatment that uses drugs or other substances to...

What is the current status of trial NCT02094872?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 49 participants. The study started on 2014-05. Estimated completion is 2018-12.

What interventions are being tested in trial NCT02094872?

The interventions under investigation include: laboratory biomarker analysis (OTHER), cytology specimen collection procedure (OTHER), quality-of-life assessment (OTHER), therapeutic procedure (PROCEDURE), MEK 162 therapy or molecularly targeted therapy (DRUG).

Who is sponsoring clinical trial NCT02094872?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02094872's enrollment target sits among peer trials

49 1261st of 2000 higher than 736 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02094872, the US trial registry maintained by the National Library of Medicine. NCT02094872 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.