VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 27 of 34

COMPLETED NA

Combined Neural and Behavioral Therapies to Enhance Stroke Recovery

NCT00929656

COMPLETED Phase 3

Prasugrel for Prevention of Early Saphenous Vein Graft Thrombosis

NCT01560780

COMPLETED

Retinal Vessel Measurements as Clinically Useful Predictors in Veterans

NCT01772173

COMPLETED Phase 2

Integrated Alcohol Disorder and PTSD Treatment

NCT01601067

COMPLETED NA

Effects of Exercise Intervention on Aging-related Motor Decline

NCT01787292

COMPLETED NA

Stroke Self-Management: Effect on Function and Stroke Specific Quality of Life

NCT01507688

COMPLETED Phase 2

Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial

NCT01759771

COMPLETED NA

Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs

NCT01357577

COMPLETED NA

Exposure Therapy For Veterans With PTSD And Panic Attacks

NCT01033136

COMPLETED NA

Multimodal Exercises to Improve Leg Function After Spinal Cord Injury

NCT01740128

COMPLETED Phase 2

Inflammation in Chronic Kidney Disease and Cardiovascular Disease - The Role of Genetics and Interleukin-1 Receptor Antagonist (IL-1ra)

NCT00897715

COMPLETED NA

Telemedicine Intervention to Improve Physical Function

NCT01639469

COMPLETED NA

Using Stories to Address Disparities in Hypertension

NCT01276197

COMPLETED NA

Acceptance-based Group Intervention for Binge Eating

NCT01757847

COMPLETED Phase 1

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277

COMPLETED

Evaluation of VLER-Indiana Health Information Exchange Demonstration Project

NCT01446705

COMPLETED Phase 3

Rivastigmine Patch in Veterans With Cognitive Impairment Following TBI

NCT01670526

COMPLETED Phase 3

VA Augmentation and Switching Treatments for Improving Depression Outcomes

NCT01421342

TERMINATED NA

Health Behavior Change for Hospitalized Veterans

NCT01602172

COMPLETED Phase 2

Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of Mifepristone

NCT01739335

COMPLETED NA

Investigations of the Optimum Serum Bicarbonate Level in Renal Disease.

NCT01574157

COMPLETED NA

Vestibular Rehabilitation and Dizziness

NCT01729039

COMPLETED NA

Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression

NCT01572389

COMPLETED NA

A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder

NCT01569022

COMPLETED NA

MISSION-Vet HUD-VASH Implementation Study

NCT01430741

COMPLETED NA

PCI Alternative Using Sustained Exercise

NCT03520400

COMPLETED

Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Centers

NCT01350479

COMPLETED Phase 2

IOK Treatment Study

NCT01605799

COMPLETED Phase 1

Reducing Dyskinesia in Parkinson's Disease With Omega-3 Fatty Acids

NCT01563913

COMPLETED NA

Targeted Intervention to Improve Medication Adherence in Cognitively Impaired Patients With HF (TARGET)

NCT01602731

COMPLETED

Stroke Swallowing Screening Tool Validation

NCT01559649

COMPLETED Phase 4

Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization

NCT04222699

COMPLETED NA

Using Peer Mentors to Support PACT Team Efforts to Improve Diabetes Control

NCT01651117

TERMINATED Phase 3

rTMS for the Treatment of Chronic Pain in GW1 Veterans

NCT01608321

COMPLETED Phase 3

A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors

NCT01265550

COMPLETED NA

Maintenance After Initiation of Nutrition TrAINing

NCT01357551

COMPLETED NA

Tailored Activity Program-Veterans Affairs

NCT01357564

COMPLETED

Biomechanical Validation of the Transfer Assessment Instrument (TAI)

NCT01183546

COMPLETED NA

Motivational Interviewing to Prevent Suicide in High Risk Veterans

NCT01544127

COMPLETED NA

Titrated Disease Management for Patients With Hypertension

NCT01390272

COMPLETED NA

Randomized Trial to Test the "Coordinated Care for Health Promotion and Activities in Parkinson's Disease" Intervention in the VA

NCT01532986

COMPLETED NA

The Effectiveness of rTMS in Depressed VA Patients

NCT01191333

COMPLETED Phase 2

Resistance Training and Testosterone After Spinal Cord Injury

NCT01652040

COMPLETED NA

Group Treatment for PTSD: A Randomized Clinical Trial With Veterans

NCT01544088

COMPLETED NA

Preparing Older Veterans With Serious and Chronic Illness for Decision Making

NCT01550731

COMPLETED NA

Preventing Violence Among Veterans in Substance Use Disorder Treatment

NCT01337973

COMPLETED Phase 2

Effectiveness of onaBoNT-A vs Oral Tamsulosin in Men With BPH and LUTS

NCT01589263

TERMINATED Phase 4

Functional Vision in TBI

NCT01214070

COMPLETED

Evaluation of Peer Telephone Cessation Counseling for Smokers

NCT01359371

TERMINATED Phase 2

The Role of Ghrelin in Cancer Cachexia

NCT01505764

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.