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NCT01740128 · ClinicalTrials.gov registry record · NA
Multimodal Exercises to Improve Leg Function After Spinal Cord Injury
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
NCT01740128: Completed NA study, sponsored by VA Office of Research and Development.
NCT01740128 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01740128, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
Study Summary
Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'. Typical exercise programs focus on keeping muscles strong and flexible, but don't usually focus on helping patients control their muscles. The investigators' exercise research study will compare two different programs with the specific goal of improving conscious control of patients' muscles below the injury. This study focuses on those with 'chronic' SCI - the injury occurred at least one year prior to enrolling. This is a single center study taking place in the Bronx, NY. The first phase of the study will be observational - the investigators will analyze which nerve connections might remain partially intact through the injury (even if the nerves aren't consciously controlled). Participants with all severity of SCI may participate in this first phase. The second phase of the study will involve people who retain at least slight ability to move their legs and the ability to move the arms against gravity. Each person will undergo two different exercise rehabilitation strategies: weight-supported treadmill training; and balance training combined with skilled arm or hand exercises. The investigators will compare the effects of these exercise programs on a variety of outcomes, including gait speed, balance, strength, and muscle activation in response to brain stimulation. The investigators hypothesize that participants with chronic SCI undergoing combined balance/arm/hand training will show improved outcomes when compared to traditional gait or balance training.
Primary Outcome
Change between baseline and Evaluation #2 in motor evoked potential area in the tibialis anterior muscle.
Interventions
- DEVICE Robotic body weight supported treadmill training
- OTHER Harness-supported multimodal balance training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2013-01-01 |
| Est. Completion | 2017-10-23 |
| Phase | NA |
What the finished NCT01740128 record still lists
NCT01740128 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Robotic body weight supported treadmill training is the first listed.
NCT01740128 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01740128 about?
NCT01740128 is a clinical study titled "Multimodal Exercises to Improve Leg Function After Spinal Cord Injury". Many people with spinal cord injury (SCI) retain at least some movement below their injury, but their muscles often have a 'mind of their own'. Typical exercise programs focus on keeping muscles strong and flexible, but don't usually focus on helping patients control their muscles. The investigators...
What is the current status of trial NCT01740128?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2013-01-01. Estimated completion is 2017-10-23.
What interventions are being tested in trial NCT01740128?
The interventions under investigation include: Robotic body weight supported treadmill training (DEVICE), Harness-supported multimodal balance training (OTHER).
Who is sponsoring clinical trial NCT01740128?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01740128's enrollment target sits among peer trials
21 1762nd of 2000 higher than 233 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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