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NCT01759771 · ClinicalTrials.gov registry record · Phase 2

Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial

A Phase 2 study, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 2
Development phase
130
Enrollment target

NCT01759771: Completed Phase 2 study, sponsored by VA Office of Research and Development.

NCT01759771 is a Phase 2 study that has completed, run by VA Office of Research and Development. The registered enrollment target is 130 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01759771, a Phase 2 study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 2
Development phase
130 participants
Enrollment target

Study Summary

Vitamin D promotes the differentiation of prostate cancer cells and maintains the differentiated phenotype of prostate epithelial cells. The results of the investigators' clinical studies indicate that vitamin 1,25 dihydroxyvitamin D3 (VD3) supplementation results in a decrease of positive cancer cores at repeat biopsy in subjects with low-risk prostate cancer. The investigators hypothesize that Veterans who have early-stage prostate cancer and who take vitamin D3 at 4000 international units per day (intervention group) will show an improvement in the number of positive cores and in Gleason score at repeat biopsy, and a decreased likelihood of undergoing definitive treatment (prostatectomy or radiation therapy), compared to Veteran subjects taking placebo (control group).

Interventions

  • DRUG Placebo
  • DRUG Vitamin D3

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2013-01-03
Est. Completion 2020-05-11
Phase Phase 2

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT01759771

The ClinicalTrials.gov registry entry for NCT01759771 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01759771 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01759771 about?

NCT01759771 is a clinical study titled "Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial". Vitamin D promotes the differentiation of prostate cancer cells and maintains the differentiated phenotype of prostate epithelial cells. The results of the investigators' clinical studies indicate that vitamin 1,25 dihydroxyvitamin D3 (VD3) supplementation results in a decrease of positive cancer co...

What is the current status of trial NCT01759771?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 130 participants. The study started on 2013-01-03. Estimated completion is 2020-05-11.

What interventions are being tested in trial NCT01759771?

The interventions under investigation include: Placebo (DRUG), Vitamin D3 (DRUG).

Who is sponsoring clinical trial NCT01759771?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.