VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 21 of 34

COMPLETED NA

Cognitive Training in the Treatment of AUD

NCT02664038

COMPLETED NA

Primary Care Intervention to Reduce Prescription Opioid Overdoses

NCT02464410

COMPLETED Phase 1

Biological Signatures, Probiotic Among Those With mTBI and PTSD

NCT02723344

COMPLETED NA

Integrating Pharmacogenetics In Clinical Care

NCT02871934

COMPLETED NA

Powered Exoskeletons in Persons With SCI

NCT02658656

TERMINATED NA

Long-Term Effectiveness of Walking Training in Patients With Knee Osteoarthritis

NCT02767570

COMPLETED NA

Telehealth Cognitive Behavioral Therapy for Depression in Parkinson's Disease (PD)

NCT02475954

COMPLETED NA

Evaluation of Web-Based CBT for Women Veterans With PTSD

NCT02917447

COMPLETED NA

Orthotic Dose Response Study

NCT02629731

COMPLETED NA

ASPIRE Cognitive Enhancement Study

NCT02657954

COMPLETED NA

Physical Activity Behavior Change for Older Adults After Dysvascular Amputation

NCT02738086

COMPLETED NA

A Proactive Walking Trial to Reduce Pain in Black Veterans

NCT01983228

COMPLETED NA

STepped Exercise Program for Knee OsteoArthritis

NCT02653768

COMPLETED NA

Encouraging Patient-Centered Communication in Clinical Video Telehealth Visits

NCT02522494

COMPLETED Phase 3

Diuretic Comparison Project

NCT02185417

COMPLETED NA

Using Emotion Regulation to Decrease Aggression in Veterans With PTSD

NCT02724787

COMPLETED

Amyloidopathy, Cholinopathy, Dopamine Responsiveness and Freezing of Gait in PD

NCT03647137

COMPLETED NA

Exercise Training in Heart Failure: Changes in Cardiac Structure and Function

NCT02275819

COMPLETED NA

Protocol-guided Rapid Evaluation of Veterans Experiencing New Transient Neurological Symptoms

NCT02769338

COMPLETED Phase 2

CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders

NCT02500602

TERMINATED Phase 4

Albuterol to Improve Respiratory Strength in SCI

NCT02508311

COMPLETED NA

Adjunctive Mood Management for Telephone-based Smoking Cessation

NCT02500589

COMPLETED NA

Delivery Models of Caregiver Support and Education

NCT02368132

COMPLETED NA

CAM in Veterans With Gulf War Illnesses

NCT02180243

COMPLETED NA

Neural Adaptation After Tendon Transfer and Training in Tetraplegia

NCT02768103

COMPLETED

Shared Health Appointments and Reciprocal Enhanced Support

NCT02132676

COMPLETED Phase 2

CAP-Ketamine for Antidepressant Resistant PTSD

NCT02655692

COMPLETED NA

Justice-Involved Veterans and Moral Reconation Therapy

NCT02524171

COMPLETED NA

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

NCT02697435

COMPLETED NA

Improving Function in Older Veterans With Hospital-Associated Deconditioning

NCT02696382

COMPLETED NA

TOP Implementation Project

NCT02737098

COMPLETED NA

Cognitive-Behavioral Therapy for Veterans With TBI

NCT02658669

COMPLETED Early Phase 1

Virtual Reality Rehabilitation for Individuals With Lower Limb Amputation

NCT02328859

COMPLETED Phase 1

Theta-Burst Neuromodulation for PTSD

NCT02769312

TERMINATED NA

Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea

NCT02721251

COMPLETED NA

Motivational Negative Symptoms in Schizophrenia: Intervention and Biomarkers

NCT02386605

COMPLETED NA

Crisis Line Facilitation

NCT02459587

COMPLETED NA

A Patient-Centered Intervention to Improve Opioid Safety

NCT02791399

COMPLETED NA

Regional Data Exchange to Improve Care for Veterans After Non-VA Hospitalization

NCT02689076

COMPLETED NA

Enhancing STDP After Spinal Cord Injury

NCT02701777

COMPLETED NA

Quality Improvement and Personalization for Statins

NCT02820870

COMPLETED NA

Shifting Rehabilitation Paradigms in Skilled Nursing Facilities

NCT02927171

TERMINATED Phase 4

Optimal Treatment for Recurrent Clostridium Difficile

NCT02667418

COMPLETED

Maintaining Independence and Sobriety Through Systems Integration, Outreach, and Networking

NCT02942979

COMPLETED NA

Effect of Exercise in Parkinsonism

NCT02598973

COMPLETED NA

eHealth Partnered Evaluation Initiative

NCT02665468

COMPLETED NA

Cognitive Behavior Therapy for Work Success in Veterans With Mental Illness: A Pre-post Efficacy Study

NCT01918774

COMPLETED NA

Neurophysiological and Kinematic Predictors of Response in Chronic Stroke

NCT02658630

COMPLETED NA

Fatiguing Arm Exercise Following Stroke

NCT03194464

COMPLETED NA

Dietary Carbohydrate and GERD in Veterans

NCT02384551

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.