VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Post Traumatic Stress Disorder, with 45 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 75/100

1,108 of 1,180 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,668 total, page 20 of 34

COMPLETED NA

Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format

NCT02665052

COMPLETED NA

Treatment of Sleep-disordered Breathing in Patients With SCI

NCT02830074

COMPLETED NA

Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

NCT03100539

TERMINATED Phase 2

Testosterone Plus Finasteride Treatment After Spinal Cord Injury

NCT02248701

COMPLETED NA

Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm

NCT03115346

COMPLETED NA

A Novel Mechanics-based Intervention to Improve Post-stroke Stability

NCT02964039

COMPLETED Phase 4

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

NCT02579096

COMPLETED NA

An RCT of a Primary Care-Based PTSD Intervention: Clinician-Supported PTSD Coach

NCT02685358

COMPLETED NA

Coordination Toolkit and Coaching Project

NCT03063294

COMPLETED

The "AIM Study": Investigating Whether Actigraphy and Ideation Measures Can Promote Patient Safety

NCT03080168

COMPLETED

Falls in Older Persons With Limb Loss

NCT03670004

COMPLETED NA

Telephone-linked Home-based Exercise Training in PD

NCT02898740

COMPLETED NA

Piloting Prehabilitation Before Abdominal Surgery

NCT03040336

COMPLETED NA

Transcranial Electrical Stimulation for mTBI

NCT03244475

COMPLETED NA

Evaluating Evidence-Based Quality Improvement of Comprehensive Women's Health Care Implementation in Low-Performing VAs

NCT03238417

COMPLETED NA

Metabolic Syndrome and Fall Risk

NCT02633891

COMPLETED NA

Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke

NCT02856035

COMPLETED NA

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

NCT02641496

COMPLETED NA

Reducing Colorectal Cancer Death Through Mailed Outreach Screening

NCT02584998

TERMINATED NA

Muscle Vibration in MS to Improve Walking

NCT03403413

TERMINATED

Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles

NCT03440008

COMPLETED NA

Impact of a Mobility Program

NCT02674503

COMPLETED NA

Exercise Effects on Word Learning

NCT03370471

COMPLETED NA

Palliative Care Interventions for Outpatients Newly Diagnosed With Lung Cancer: Phase II

NCT03007953

TERMINATED Phase 1

Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms

NCT02846883

TERMINATED Phase 4

Prazosin and Cerebrospinal Fluid (CSF) Biomarkers in Mild Traumatic Brain Injury (mTBI)

NCT03221751

COMPLETED NA

Mindfulness Training in Healthy Older Veterans

NCT02816723

COMPLETED NA

Caring Others Increasing EngageMent in PACT

NCT02328326

COMPLETED NA

Cardiovascular Risk Screening and Risk Reduction in Women Vets

NCT02991534

COMPLETED NA

ACT for Life: a Brief Intervention for Maximizing Recovery After Suicidal Crises

NCT02751983

COMPLETED

PrOVE QUERI Project #1

NCT02765412

COMPLETED NA

Mindful Stress Reduction in Diabetes Self-management Education for Veterans

NCT02928952

COMPLETED NA

Improving Rehabilitation Outcomes After Total Hip Arthroplasty

NCT02920866

COMPLETED NA

Improving Functions in Veterans With Post-traumatic Peripheral Neuropathic Pain

NCT02979925

COMPLETED NA

Cognitive Behavioral Therapy for Insomnia for Gulf War Illness

NCT02782780

COMPLETED NA

Peer Enhanced Prolonged Exposure

NCT02818114

COMPLETED NA

Multimodel Exercise and Weight Loss in Older Obese Veterans With Dysmobility

NCT02806336

COMPLETED NA

Cognitive-Behavioral Conjoint Therapy (CBCT) Project

NCT02720016

COMPLETED NA

One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology

NCT02844946

COMPLETED

Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program

NCT03296280

COMPLETED NA

Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)

NCT02774642

COMPLETED Phase 2

Effects of Broccoli Sprout Extract on Allergy Rhinitis

NCT02885025

COMPLETED NA

Learn, Engage, Act, Process (LEAP) for MOVE!

NCT02825680

COMPLETED NA

Optimizing Dementia Care

NCT02585232

COMPLETED NA

GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures

NCT03462680

COMPLETED NA

Integrating Caregiver Support Into MS Care

NCT02835677

COMPLETED NA

De-implementing Inhaled Steroids to Improve Care and Safety in COPD

NCT02896257

COMPLETED NA

Benefits of Physical Exercise in Schizophrenia

NCT02716584

COMPLETED NA

Advancing Symptom Alleviation With Palliative Treatment

NCT02713347

COMPLETED NA

Comparative Effectiveness of Two Treatments for Veterans With PTSD

NCT02586064

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: Post Traumatic Stress Disorder (45 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

VA Office of Research and Development: open-pipeline peers nationwide

Peers matched on 1,668 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 10%12%14%16%18% Total trials Recruiting share VA Office of Research and DevelopmentUniversity of California, San FranciscoDuke UniversityStanford UniversityWashington University School of MedicineUniversity of South FloridaImmunityBioOld Dominion UniversityTexas Tech University
VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

VA Office of Research and Development sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,668 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this VA Office of Research and Development page

1,668 registered trials is a research-attention snapshot, not an endorsement of VA Office of Research and Development or any single study.

  • 291 of VA Office of Research and Development's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Post Traumatic Stress Disorder is the condition VA Office of Research and Development studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Post Traumatic Stress Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. VA Office of Research and Development pipeline card: 1,668 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.