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NCT02701777 · ClinicalTrials.gov registry record · NA
Enhancing STDP After Spinal Cord Injury
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 62
- Enrollment target
NCT02701777: Completed NA study, sponsored by VA Office of Research and Development.
NCT02701777 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 62 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02701777, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 62 participants
- Enrollment target
Study Summary
The overall goal is to develop new clinical approaches to restore limb function after spinal cord injury (SCI). Corticospinal tract (CST) axons are involved in controlling limb function. Paired pulse induced spike-timing dependent plasticity (STDP) enhances synaptic strength between residual CST axons and spinal motoneurons (SMNs) resulting in temporary improvements in limb function in humans with incomplete SCI. Motor training will be combined with paired-pulse STDP stimulation to further enhance plasticity and behavioral recovery.
Primary Outcome
The Graded Redefined Assessment of Strength Sensibility and Prehension (GRASSP) assessment is a standardized test of functional abilities of the hand. We measure time required to complete the GRASSP test for upper extremity functional assessment. 10-m walk test is used to measure walking speed for lower extremity functional assessment. The time to complete the task is assessed in seconds for both measurements and normalized as percentage of Baseline. Normalization to baseline allows comparison a
Interventions
- BEHAVIORAL Training
- OTHER STDP
- OTHER Sham STDP
- OTHER Multisite-STDP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2016-03-01 |
| Est. Completion | 2020-10-30 |
| Phase | NA |
What the finished NCT02701777 record still lists
NCT02701777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 4 interventions - of which Training is the first listed.
NCT02701777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02701777 about?
NCT02701777 is a clinical study titled "Enhancing STDP After Spinal Cord Injury". The overall goal is to develop new clinical approaches to restore limb function after spinal cord injury (SCI). Corticospinal tract (CST) axons are involved in controlling limb function. Paired pulse induced spike-timing dependent plasticity (STDP) enhances synaptic strength between residual CST axo...
What is the current status of trial NCT02701777?
This trial is currently completed. It is a NA study. The enrollment target is 62 participants. The study started on 2016-03-01. Estimated completion is 2020-10-30.
What interventions are being tested in trial NCT02701777?
The interventions under investigation include: Training (BEHAVIORAL), STDP (OTHER), Sham STDP (OTHER), Multisite-STDP (OTHER).
Who is sponsoring clinical trial NCT02701777?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02701777's enrollment target sits among peer trials
62 1157th of 2000 higher than 837 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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