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NCT04999995 · ClinicalTrials.gov registry record

Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure

A clinical trial, sponsored by VA Office of Research and Development.

Completed
Registry status
17
Enrollment target

NCT04999995: Completed study, sponsored by VA Office of Research and Development.

NCT04999995 is a clinical trial that has completed, run by VA Office of Research and Development. The registered enrollment target is 17 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04999995 has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
17 participants
Enrollment target

Study Summary

Autophagy is considered an important component of Heart failure progression. Deubiquitination enzymes play an important role in autophagy. An important regulatory process within the autophagy pathway is ubiquitination. Ubiquitination targets proteins for degradation. On the contrary, de-ubiquitinating proteins (such as UCHL1) reverses this process. Studies have demonstrated deubiquitination to be linked to certain pathological processes, such as heart failure. UCHL1 will be examined as a potential marker of disease progression in acute decompensated heart failure.

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2021-06-01
Est. Completion 2025-03-17

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT04999995

The ClinicalTrials.gov registry entry for NCT04999995 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT04999995 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04999995 about?

NCT04999995 is a clinical study titled "Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure". Autophagy is considered an important component of Heart failure progression. Deubiquitination enzymes play an important role in autophagy. An important regulatory process within the autophagy pathway is ubiquitination. Ubiquitination targets proteins for degradation. On the contrary, de-ubiquitinati...

What is the current status of trial NCT04999995?

This trial is currently completed. The enrollment target is 17 participants. The study started on 2021-06-01. Estimated completion is 2025-03-17.

Who is sponsoring clinical trial NCT04999995?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.