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NCT07222046 · ClinicalTrials.gov registry record · NA
Spinal Neurorehabilitation for Veterans With SCI
A NA study, sponsored by VA Office of Research and Development.
- Not yet
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT07222046: Clinical Trial NA study, sponsored by VA Office of Research and Development.
NCT07222046 is a NA study that has not yet begun recruiting, run by VA Office of Research and Development. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07222046, a NA study, has not yet begun recruiting, sponsored by VA Office of Research and Development.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Chronic spinal cord injury (SCI) is a debilitating disorder in Veterans and the broader U.S. population that does not have a cure. Veterans with severe SCI demonstrate permanent loss of sensory and motor function below their injury resulting in decreased quality of life and independence. Recently, electrical spinal neuromodulation has emerged as a potential approach to restore voluntary motor function and locomotion in persons with chronic SCI. However, spinal neuromodulation has yet to translate to clinical use due to small sample sizes in research studies and a lack of information on which patients would benefit. Here, the investigators propose a novel approach to evaluate the priorities and barriers faced by Veterans with SCI to use spinal neuromodulation, understand the neural connections remaining in Veterans with severe SCI, and determine potential functional improvements using non-invasive spinal neuromodulation technology. This research represents the first step towards deploying techniques that could dramatically improve function and quality of life for Veterans with SCI.
Primary Outcome
Spared region volume at the injury site as assessed by spine MRI will be compared with clinical SCI score as measured by the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) exam.
Interventions
- DEVICE Transcutaneous Spinal Stimulation
- DIAGNOSTIC_TEST Neurophysiological and anatomical testing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-01-23 |
| Est. Completion | 2030-12-31 |
| Phase | NA |
What is known before NCT07222046 opens enrollment
NCT07222046 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Transcutaneous Spinal Stimulation is the first listed.
NCT07222046 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07222046 about?
NCT07222046 is a clinical study titled "Spinal Neurorehabilitation for Veterans With SCI". Chronic spinal cord injury (SCI) is a debilitating disorder in Veterans and the broader U.S. population that does not have a cure. Veterans with severe SCI demonstrate permanent loss of sensory and motor function below their injury resulting in decreased quality of life and independence. Recently, e...
What is the current status of trial NCT07222046?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-01-23. Estimated completion is 2030-12-31.
What interventions are being tested in trial NCT07222046?
The interventions under investigation include: Transcutaneous Spinal Stimulation (DEVICE), Neurophysiological and anatomical testing (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07222046?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07222046's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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