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NCT07180654 · ClinicalTrials.gov registry record
Menstrual Cycle TMS Plasticity Pilot
A clinical trial of Cortical Activation, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT07180654: Recruiting study of Cortical Activation, sponsored by University of Pennsylvania.
NCT07180654 is a study of Cortical Activation that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 100 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07180654, a study of Cortical Activation, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Aim 1: Assess how menstrual cycle phase affects motor cortex plasticity in females. Aim 2: Compare motor cortex plasticity between males and females across the same time points, identifying potential sex differences in TMS response. Aim 3: Examine associations between serum hormone levels and TMS-induced plasticity within and between sexes.
Primary Outcome
Single-pulse TMS: Cortical excitability curves will be measured before and after a single 1800-pulse train of iTBS. Motor Evoked Potentials (MEPs) will be recorded from the right FDI muscle at 7 distinct intensities ranging from -20% to + 40% of MT. Single pulses will be delivered once every 10±3 seconds to the left motor cortex at random intensities in the above range to avoid habituation across pulses. Across the session, a total of 70 pulses will be delivered before and after iTBS, 10 at each
Conditions Studied
Interventions
- DEVICE transcranial magnetic stimulation
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-12-15 |
| Est. Completion | 2028-10-31 |
What NCT07180654 shows while recruiting
NCT07180654 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Cortical Activation appearing as the primary indexed condition, and to 1 intervention - of which transcranial magnetic stimulation is the first listed.
NCT07180654 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07180654 about?
NCT07180654 is a clinical study titled "Menstrual Cycle TMS Plasticity Pilot". Aim 1: Assess how menstrual cycle phase affects motor cortex plasticity in females. Aim 2: Compare motor cortex plasticity between males and females across the same time points, identifying potential sex differences in TMS response. Aim 3: Examine associations between serum hormone levels and TMS-...
What is the current status of trial NCT07180654?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2025-12-15. Estimated completion is 2028-10-31.
What conditions does trial NCT07180654 study?
This clinical trial studies the following conditions: Cortical Activation.
What interventions are being tested in trial NCT07180654?
The interventions under investigation include: transcranial magnetic stimulation (DEVICE).
Who is sponsoring clinical trial NCT07180654?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07180654 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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