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NCT07199764 · ClinicalTrials.gov registry record · Phase 2

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

A Phase 2 study of Pancreatic Ductal Adenocarcinoma, sponsored by University of Pennsylvania.

Recruiting
Registry status
Phase 2
Development phase
100
Enrollment target
1
Study location

NCT07199764 is a Phase 2 study of Pancreatic Ductal Adenocarcinoma that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 100 participants, below the 599-participant average among 84 other Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07199764, a Phase 2 study of Pancreatic Ductal Adenocarcinoma, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

Phase II, open-label, single-arm study of CD40/Dectin-1 immunotherapy as maintenance treatment in patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not progressed following 4-6 months of first line (1L) chemotherapy.

Interventions

  • DRUG Odetiglucan
  • DRUG Mitazalimab

Study Locations (1)

Pennsylvania

  • Hospital of the University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-11-25
Est. Completion 2028-12
Phase Phase 2

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT07199764

The ClinicalTrials.gov registry entry for NCT07199764 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 599-participant average among 84 other Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (83% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreatic Ductal Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Odetiglucan is the first listed.

NCT07199764 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT07199764 about?

NCT07199764 is a clinical study titled "Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer". Phase II, open-label, single-arm study of CD40/Dectin-1 immunotherapy as maintenance treatment in patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not progressed following 4-6 months of first line (1L) chemotherapy.

What is the current status of trial NCT07199764?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2025-11-25. Estimated completion is 2028-12.

What conditions does trial NCT07199764 study?

This clinical trial studies the following conditions: Pancreatic Ductal Adenocarcinoma.

What interventions are being tested in trial NCT07199764?

The interventions under investigation include: Odetiglucan (DRUG), Mitazalimab (DRUG).

Who is sponsoring clinical trial NCT07199764?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07199764 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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