University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 12 of 16

COMPLETED NA

Laser Based Focal Ablation of Low Grade Prostate Cancer

NCT01192438

COMPLETED

Understanding Sleep in Hospitalized Older Patients

NCT01057823

COMPLETED

Development and Validation of a Tool to Measure Hand-off Quality

NCT01059942

COMPLETED Phase 1

A Genotype-guided Study of Irinotecan Administered in Combination With 5-fluorouracil/Leucovorin (FOLFIRI) and Bevacizumab in Advanced Colorectal Cancer Patients

NCT01183494

COMPLETED NA

Effect of Omega-3 Supplementation During Pregnancy on Regulation of Stress

NCT01158976

COMPLETED

Investigation of Genetic Determinants of Capecitabine Toxicity

NCT00977119

COMPLETED NA

Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes

NCT01136785

COMPLETED NA

Staging of Axillary Lymph Nodes Using the PEM Flex Solo II Pet Scanner in Patients With Breast Cancer

NCT01011946

COMPLETED NA

Intraoperative Bleeding During Endoscopic Sinus Surgery

NCT01014728

COMPLETED NA

Vitamin D for Chronic Sinusitis

NCT01007799

COMPLETED Phase 4

Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms

NCT01007253

COMPLETED

Effect of Prednisone onTregs and TH17

NCT01002313

TERMINATED NA

Role of Positron Emission Mammography (PEM) Flex Solo II Positron Emission Tomography (PET) Scanner in Evaluating Neoadjuvant Chemotherapy Response in Patients With Breast Cancer

NCT01012440

COMPLETED NA

Effective Treatment of Sleep Apnea in Prediabetes to Reduce Cardiometabolic Risk

NCT01156116

COMPLETED

Genetic Determinants of Response to Neoadjuvant Cisplatin-based Chemotherapy in Urothelial Cancer

NCT01206426

COMPLETED

Investigation of Cisplatin-Related Kidney Toxicity

NCT00984035

COMPLETED Phase 2

N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers

NCT00967005

COMPLETED

Ultrasound Determination of Needle Depth in Epidurals in Adult Patients

NCT00981916

TERMINATED Phase 4

Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)

NCT01059929

COMPLETED Phase 4

Clinical and Economic Implications of Genetic Testing for Warfarin Management

NCT00964353

TERMINATED

Cardiometabolic Risk of Shiftwork

NCT01264913

COMPLETED NA

Teaching Use of Respiratory Inhalers (TURI)

NCT01456494

COMPLETED

Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast Cancer

NCT01706432

COMPLETED Phase 2

Tolcapone Treatment of Pathological Gambling

NCT00927563

TERMINATED NA

Safety and Efficacy of Computer Assisted Surgery for Use in Vascular Surgery Procedures

NCT01136811

COMPLETED Phase 3

Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)

NCT00952120

COMPLETED Phase 1

Study of Stereotactic Body Radiation Therapy in Patients With Intact Pancreatic Cancer

NCT01342354

COMPLETED Phase 4

Stress Testing and Cardiac Magnetic Resonance

NCT00871260

TERMINATED Phase 1

Initiating Transdermal Estradiol Therapy in Turner's Syndrome

NCT00870220

TERMINATED Phase 2

The Synergistic Metastases Annihilation With Radiotherapy and Docetaxel (Taxotere) [SMART] Trial for Non-Small Cell Lung Cancer (NSCLC)

NCT00887315

COMPLETED NA

Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging

NCT00857792

COMPLETED Phase 2

Memantine in the Treatment of Kleptomania

NCT00880685

COMPLETED

Cardiovascular Complications of Sickle Cell Disease

NCT01044901

COMPLETED NA

Individual Differences in Diabetes Risk: Role of Sleep Disturbances

NCT00989976

COMPLETED

Vitamin D Levels in Children Undergoing Adenotonsillectomies and Controls

NCT00829972

COMPLETED NA

Improving Diabetes Care and Outcomes on the South Side of Chicago

NCT01087073

COMPLETED NA

MRSA Colonization and Control in the Dallas County Jail

NCT00785200

COMPLETED

Lysosomal Storage Disease: Health, Development, and Functional Outcome Surveillance in Preschool Children

NCT01938014

COMPLETED Phase 2

Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries

NCT00829296

COMPLETED NA

Continuous Venovenous Hemofiltration Versus Continuous Venovenuous Hemodialysis

NCT01062984

TERMINATED Phase 3

Randomized Trial of Ciprofloxacin Versus Observation for Men With Elevated Prostate Specific Antigen (PSA)

NCT00840294

COMPLETED NA

Immunogenicity and Safety of HPV Vaccine Gardasil in Young Women

NCT00786409

COMPLETED Phase 4

Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen

NCT00791973

COMPLETED NA

Susceptibility to Pathological Gambling

NCT01528982

COMPLETED

Individual Differences in Diabetes Risk: Role of Slow WaveSleep

NCT00989378

COMPLETED NA

Sleep Disturbances as a Risk Factor in Chronic Kidney Disease

NCT00817427

COMPLETED Phase 1

Primary Care Patients With Depression for Internet-Based Social Support

NCT00886730

COMPLETED

Celiac Disease Database

NCT01172665

COMPLETED

ACT-HF: Attention, Cognition and Self-Management in Heart Failure

NCT01064765

COMPLETED Phase 2

Naltrexone in the Treatment of Trichotillomania

NCT00775229

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Chicago pipeline card: 796 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.