University of Chicago

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Chicago sits in the top decile of US sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count).

796 total trials 158 currently recruiting 451 completed early-phase tilt top decile by trial count

University of Chicago: 796 sponsored US clinical trials, 158 recruiting.

University of Chicago sponsors 796 registered US clinical trials on ClinicalTrials.gov, 158 of them currently recruiting, and 451 completed. 67 of these trials are in Phase 3-4 (later-stage) and 293 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 11 trials.

Top-decile sponsor footprint

University of Chicago ranks in the top decile of sponsors by registered trial count (#41 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 40/100

451 of 562 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (80.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

796 total, page 10 of 16

COMPLETED Phase 1

Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

NCT02046421

COMPLETED Early Phase 1

The Effects of Buprenorphine on Responses to Verbal Tasks

NCT01860287

TERMINATED Phase 2

The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass

NCT01928082

COMPLETED

DBS Frequency on Swallowing Function in Parkinson's Disease

NCT01935011

COMPLETED NA

Sleep for Inpatients: Empowering Staff to Act

NCT02025959

COMPLETED NA

Comparing the Outcomes Between Rotator Cuff Repair With and Without Suprascapular Nerve Decompression

NCT02107573

COMPLETED

Parkinsonism in Spinocerebellar Ataxia Type 6

NCT01934998

COMPLETED NA

Use of Motivational Interviewing to Increase Contraception Use Among Young Women

NCT01881321

COMPLETED NA

Impact of Video Intervention on Postabortal Uptake of Long Acting Reversible Contraception (LARC)

NCT01945385

TERMINATED

Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer

NCT01949740

TERMINATED Phase 1

A Pilot and Feasibility Study of Fecal Microbiota Transplantation for Ulcerative Colitis

NCT02058524

COMPLETED NA

Outcomes of Biceps Tenodesis or Labral Repair for Treatment of Type 2 Superior Labrum Anterior and Posterior Lesions

NCT02107547

COMPLETED NA

Comparison of Outcomes Between Biceps Tenotomy and Tenodesis in the Treatment of the Long Head of the Biceps Pathology

NCT02107586

COMPLETED NA

Patient Support During Surgical Abortion

NCT01937988

COMPLETED Phase 1

PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

NCT01816984

COMPLETED Phase 2

Inositol in Trichotillomania

NCT01875445

COMPLETED Phase 2

Double-Blind Treatment of Major Depressive Disorder With Vilazodone

NCT01742832

COMPLETED Phase 2

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

NCT01839916

COMPLETED Phase 1

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

NCT01847326

COMPLETED NA

Active vs Passive Distraction on Procedural Pain in the Pediatric Emergency Department

NCT01960166

COMPLETED NA

Communication Bridge Speech Therapy Research Study

NCT02439853

COMPLETED NA

Impact of the CommunityRx Program on Health, Service Utilization and Costs

NCT02411409

COMPLETED NA

Cannabidiol and Emotional Stimuli

NCT02902081

TERMINATED Phase 4

Dexamethasone and Lower Extremity Block Duration

NCT01756586

COMPLETED NA

MR-Guided Laser Interstitial Thermal Therapy in Treating Patients With Prostate Cancer

NCT01792024

TERMINATED Phase 2

Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer

NCT01803269

COMPLETED Phase 4

Allergic Rhinitis Changes the Sinus Microbiome

NCT01852513

COMPLETED NA

Effect of Azilsartan on Aldosterone in Postmenopausal Females

NCT01774591

COMPLETED

Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement

NCT01182220

TERMINATED NA

Dexamethasone and Block Duration in Upper Extremity

NCT01756573

TERMINATED Phase 4

Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair

NCT01756560

COMPLETED NA

Network Supported Engagement In HIV Care

NCT01726712

TERMINATED NA

Effect of Nasaleze on Nasal Challenge With Allergen

NCT01723397

COMPLETED

Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement

NCT01988766

COMPLETED Phase 2

N-Acetyl Cysteine in Pathologic Skin Picking

NCT01063348

COMPLETED NA

Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure

NCT01680783

TERMINATED Phase 1

Capecitabine and Celecoxib in Patients With Solid Cancers That Have Been Previously Treated With Standard Therapies

NCT01705106

COMPLETED Phase 1

Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT01665794

COMPLETED Phase 1

Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

NCT01791088

COMPLETED Phase 1

Azacitidine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With High-Risk Acute Myeloid Leukemia

NCT01839240

COMPLETED Phase 2

Erlotinib Hydrochloride in Treating Patients With Malignant Peritoneal Mesothelioma

NCT01592383

COMPLETED NA

Project ASPIRE Efficacy Pilot: Achieving Superior Parental Involvement for Rehabilitative Excellence

NCT01753661

TERMINATED NA

Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Measuring Effects of Pazopanib Hydrochloride in Patients With Metastatic Kidney Cancer

NCT01599832

COMPLETED Phase 2

Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer

NCT01599793

TERMINATED Phase 4

Pegylated Interferon, Ribavirin, Telaprevir in Hepatitis C Virus Infection in Orthotopic Liver Transplant Recipients

NCT01592006

COMPLETED Phase 1

Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies

NCT01643499

COMPLETED

Clinical Evaluation of Florbetapir in Primary Progressive Aphasia

NCT04726527

COMPLETED Phase 1

Busulfan-fludarabine Conditioning and T-cell Depleted Allogeneic Stem Cell Transplantation for Patients With Advanced Hematologic Malignancies

NCT00943319

COMPLETED

Pain Assessment in the Intensive Care Unit

NCT01628185

COMPLETED Phase 2

Food Effect Study of Abiraterone Acetate for Treatment of Patients With Castration-Resistant Prostate Cancer

NCT01543776

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Phase Distribution

PhaseTrial count
Phase 1 137
Phase 2 156
Phase 3 14
Phase 4 53

What is open in the University of Chicago pipeline

158 recruiting of 796 indexed (20% open); 451 completed (57%).

Phase mix: 67 late (III/IV) vs 293 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Chicago: open-pipeline peers nationwide

Peers matched on 796 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 14%16%18%20%22% Total trials Recruiting share University of ChicagoDana-Farber Cancer InstituteUniversity of California, San DiegoUniversity of UtahUniversity of Texas Southwestern Medical CenterAcera SurgicalAlign TechnologyAltruBioAlvernia University
University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Chicago sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 796 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of Chicago page

796 registered trials is a research-attention snapshot, not an endorsement of University of Chicago or any single study.

  • 158 of University of Chicago's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition University of Chicago studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Chicago pipeline card: 796 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.