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NCT01599793 · ClinicalTrials.gov registry record · Phase 2
Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer
A Phase 2 study of Recurrent Prostate Cancer and Stage IV Prostate Cancer, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 2
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT01599793: Completed Phase 2 study of Recurrent Prostate Cancer and Stage IV Prostate Cancer, sponsored by University of Chicago.
NCT01599793 is a Phase 2 study of Recurrent Prostate Cancer and Stage IV Prostate Cancer that has completed, run by University of Chicago. The registered enrollment target is 19 participants, below the 138-participant average among 21 other Recurrent Prostate Cancer trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01599793, a Phase 2 study of Recurrent Prostate Cancer and Stage IV Prostate Cancer, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to help researchers understand more about prostate cancer that has spread to the bones by using the newest magnetic resonance imaging (MRI) techniques and to better understand the effect of an experimental drug called XL184 (or cabozantinib) on bone disease. The other purposes of the study are to better understand the effect of XL184 on prostate cancer progression, bone pain, and on any cancer cells that patients may have circulating within the blood (called circulating tumor cells)
Primary Outcome
Ktrans is a measurement calculating the volume transfer constant of the contrast reagent and essentially is a measurement of vascular perfusion. To determine the effect of XL184 on the functional MRI metrics Ktrans, Ktrans parameters were measured at baseline, two week time-point, 12 weeks, and 24 weeks for disease monitoring. Change between baseline and 2 weeks reported.
Conditions Studied
Interventions
- OTHER laboratory biomarker analysis
- DRUG cabozantinib
- PROCEDURE magnetic resonance imaging
Study Locations (1)
Illinois
- University of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2012-05 |
| Est. Completion | 2018-12 |
| Phase | Phase 2 |
What the finished NCT01599793 record still lists
NCT01599793 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 138-participant average among 21 other Recurrent Prostate Cancer trials with a reported enrollment target (86% lower).
The record links to 4 conditions, with Recurrent Prostate Cancer appearing as the primary indexed condition, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT01599793 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01599793 about?
NCT01599793 is a clinical study titled "Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer". This study is being done to help researchers understand more about prostate cancer that has spread to the bones by using the newest magnetic resonance imaging (MRI) techniques and to better understand the effect of an experimental drug called XL184 (or cabozantinib) on bone disease. The other purpos...
What is the current status of trial NCT01599793?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2012-05. Estimated completion is 2018-12.
What conditions does trial NCT01599793 study?
This clinical trial studies the following conditions: Recurrent Prostate Cancer, Stage IV Prostate Cancer, Bone Metastases, Castrate Resistant Prostate Cancer.
What interventions are being tested in trial NCT01599793?
The interventions under investigation include: laboratory biomarker analysis (OTHER), cabozantinib (DRUG), magnetic resonance imaging (PROCEDURE).
Who is sponsoring clinical trial NCT01599793?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01599793 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Recurrent Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01599793's enrollment target sits among peer trials
19 16th of 21 higher than 6 of 21 other Recurrent Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Recurrent Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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