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NCT01742832 · ClinicalTrials.gov registry record · Phase 2

Double-Blind Treatment of Major Depressive Disorder With Vilazodone

A Phase 2 study, sponsored by University of Chicago.

Completed
Registry status
Phase 2
Development phase
79
Enrollment target

NCT01742832: Completed Phase 2 study, sponsored by University of Chicago.

NCT01742832 is a Phase 2 study that has completed, run by University of Chicago. The registered enrollment target is 79 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01742832, a Phase 2 study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 2
Development phase
79 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and effectiveness of vilazodone for the treatment of major depressive disorder versus citalopram. Doctors want to determine if vilazodone is effective for the treatment of major depressive disorder in those who have not responded to generic selective serotonin reuptake inhibitors (SSRI), which is a class of anti-depressant drugs such as Prozac, Lexapro, Paxil, or Zoloft. Both vilazodone and citalopram have been approved for the treatment of major depressive disorder. This research is being done because the researchers want to find out if vilazodone works in reducing the symptoms of depression significantly more than a generic SSRI.

Primary Outcome

The entire study will last 18 weeks. For the first 6 weeks, subjects will come in once every 2 weeks. For the next 4 weeks, subjects will come in once per week. For the next 6 weeks, subjects will come in once every 2 weeks. The final visit will come 2 weeks later for a total of 11 visits where the MADRS will be administered. Only the baseline and final (last observation) assessments for the outcome measure was used in determining results, thus these are the only values included. MADRS scores r

Interventions

  • DRUG Citalopram
  • DRUG Vilazodone

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2013-05
Est. Completion 2016-03
Phase Phase 2
University of Chicago

796 total trials

What the finished NCT01742832 record still lists

NCT01742832 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower).

The record links to 0 conditions, and to 2 interventions - of which Citalopram is the first listed.

NCT01742832 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01742832 about?

NCT01742832 is a clinical study titled "Double-Blind Treatment of Major Depressive Disorder With Vilazodone". The purpose of this study is to evaluate the safety and effectiveness of vilazodone for the treatment of major depressive disorder versus citalopram. Doctors want to determine if vilazodone is effective for the treatment of major depressive disorder in those who have not responded to generic selecti...

What is the current status of trial NCT01742832?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 79 participants. The study started on 2013-05. Estimated completion is 2016-03.

What interventions are being tested in trial NCT01742832?

The interventions under investigation include: Citalopram (DRUG), Vilazodone (DRUG).

Who is sponsoring clinical trial NCT01742832?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01742832's enrollment target sits among peer trials

79 884th of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01742832, the US trial registry maintained by the National Library of Medicine. NCT01742832 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.