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NCT06803745 · ClinicalTrials.gov registry record · NA
Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)
A NA study of Acute Leukemia and Acute Lymphoblastic Lymphoma, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Recruiting
- Registry status
- NA
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT06803745 is a NA study of Acute Leukemia and Acute Lymphoblastic Lymphoma that is actively recruiting participants, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 160 participants, below the 459-participant average among 37 other Acute Leukemia trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06803745, a NA study of Acute Leukemia and Acute Lymphoblastic Lymphoma, is actively recruiting participants, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- RECRUITING
- Registry status
- NA
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized phase II trial of standard-of-care reduced-intensity conditioning (RIC) with 200 versus 400 cGy of total body irradiation (TBI) in patients with acute leukemia undergoing first allogeneic blood or marrow Transplantation (BMT). The primary objective is to compare the rates of graft-versus-host disease-free and relapse-free survival (GRFS) between patients in the two cohorts.
Conditions Studied
Interventions
- RADIATION 200 cGy or 400 cGy total body irradiation (TBI)
Study Locations (1)
Maryland
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-03-27 |
| Est. Completion | 2030-09-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06803745
The ClinicalTrials.gov registry entry for NCT06803745 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 459-participant average among 37 other Acute Leukemia trials with a reported enrollment target (65% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Acute Leukemia appearing as the primary indexed condition, and to 1 intervention - of which 200 cGy or 400 cGy total body irradiation (TBI) is the first listed.
NCT06803745 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT06803745 about?
NCT06803745 is a clinical study titled "Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)". This is a randomized phase II trial of standard-of-care reduced-intensity conditioning (RIC) with 200 versus 400 cGy of total body irradiation (TBI) in patients with acute leukemia undergoing first allogeneic blood or marrow Transplantation (BMT). The primary objective is to compare the rates of gra...
What is the current status of trial NCT06803745?
This trial is currently recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2025-03-27. Estimated completion is 2030-09-30.
What conditions does trial NCT06803745 study?
This clinical trial studies the following conditions: Acute Leukemia, Acute Lymphoblastic Lymphoma.
What interventions are being tested in trial NCT06803745?
The interventions under investigation include: 200 cGy or 400 cGy total body irradiation (TBI) (RADIATION).
Who is sponsoring clinical trial NCT06803745?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06803745 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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