Roswell Park Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Roswell Park Cancer Institute sits in the top decile of US sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count).

365 total trials 57 currently recruiting 200 completed early-phase tilt top decile by trial count

Roswell Park Cancer Institute: 365 sponsored US clinical trials, 57 recruiting.

Roswell Park Cancer Institute sponsors 365 registered US clinical trials on ClinicalTrials.gov, 57 of them currently recruiting, and 200 completed. 7 of these trials are in Phase 3-4 (later-stage) and 238 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 9 trials.

Top-decile sponsor footprint

Roswell Park Cancer Institute ranks in the top decile of sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 18/100

200 of 279 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (71.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

365 total, page 6 of 8

COMPLETED Phase 1

Photodynamic Therapy Using HPPH in Treating Patients With Dysplasia, Cancer in Situ, or Invasive Cancer of the Larynx

NCT00675233

TERMINATED NA

Flaxseed in Preventing Breast Cancer in Premenopausal Women at Risk of Developing Breast Cancer

NCT00794989

TERMINATED Phase 2

Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma

NCT00625183

COMPLETED Phase 1

Cisplatin in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer or Lung Metastasis

NCT01014598

COMPLETED NA

Flaxseed, Aromatase Inhibitors and Breast Tumor Characteristics

NCT00612560

COMPLETED Phase 1

KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment

NCT00646139

COMPLETED NA

Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney Cancer

NCT00849186

COMPLETED NA

DNA Changes That Affect Vitamin D Metabolism in Patients With Colorectal Cancer Receiving Vitamin D Supplements

NCT00550563

TERMINATED Phase 2

Photodynamic Therapy Using HPPH in Treating Patients With Advanced Non-Small Cell Lung Cancer That Blocks the Air Passages

NCT00528775

COMPLETED Phase 2

Vitamin D in Treating Patients With Prostate Cancer

NCT00524680

COMPLETED NA

Breast and Cervical Cancer Educational Intervention for Latinas in Western New York

NCT01760850

TERMINATED Phase 2

Pegylated Liposomal Doxorubicin and Docetaxel in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery

NCT00524459

TERMINATED Phase 1

Sunitinib, Irinotecan, Fluorouracil, and Leucovorin In Treating Patients With Advanced Stomach Cancer or Gastroesophageal Cancer

NCT00524186

COMPLETED Phase 2

Pegfilgrastim and Rituximab in Treating Patients With Untreated, Relapsed, or Refractory Follicular Lymphoma, Small Lymphocytic Lymphoma, or Marginal Zone Lymphoma

NCT01682044

TERMINATED Phase 2

Sunitinib and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

NCT00524316

TERMINATED Phase 2

Doxorubicin Hydrochloride Liposome and Carboplatin in Treating Patients With Recurrent, Stage III, or Stage IV Primary Endometrial Cancer

NCT00470067

TERMINATED Phase 2

Erlotinib in Treating Patients With Stage III or Stage IV Pancreatic Cancer

NCT00470535

COMPLETED Phase 2

Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer

NCT00470184

COMPLETED Phase 1

Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer

NCT00537121

COMPLETED Phase 1

Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer

NCT00470496

TERMINATED Phase 2

Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT00526890

TERMINATED Phase 1

Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate Cancer

NCT00536991

TERMINATED NA

Cholecalciferol and Calcium Carbonate in Treating Patients With Colon Cancer That Has Been Removed by Surgery

NCT00470353

COMPLETED NA

High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors

NCT00536601

COMPLETED Phase 2

Bortezomib, Doxorubicin Hydrochloride Liposome, and Thalidomide as First-line Therapy in Treating Patients With Previously Untreated Stage I, II, or III Multiple Myeloma

NCT00523848

TERMINATED Phase 2

Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

NCT00524589

COMPLETED Phase 2

Erlotinib and Radiation Therapy in Treating Older Patients With Stage I, Stage II, Stage III, or Stage IV Esophageal Cancer

NCT00524121

COMPLETED

Autofluorescence Detection of Oral Malignancies and Database and Biospecimen Collection to Identify Biomarkers of Head and Neck Tumor Progression

NCT01531881

TERMINATED NA

Effect of a Low Glycemic Index Diet on Breast Density

NCT01237938

COMPLETED Phase 2

Bupropion in Helping Adults Stop Smoking

NCT00534001

COMPLETED Phase 1

Rituximab and Liposomal Doxorubicin in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

NCT00244985

COMPLETED Phase 2

Fulvestrant in Treating Patients With Advanced Prostate Cancer

NCT00244998

TERMINATED Phase 1

Paricalcitol and Zoledronate in Treating Patients With Relapsed or Refractory Multiple Myeloma or Other Plasma Cell Disorders

NCT00258258

COMPLETED Phase 2

Pemetrexed Disodium and Cisplatin in Treating Patients Who Are Undergoing Surgery for Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

NCT00248495

TERMINATED NA

Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis

NCT00524485

COMPLETED Phase 1

Selenium in Treating Patients Who Are Undergoing Brachytherapy for Stage I or Stage II Prostate Cancer

NCT00217516

COMPLETED Phase 1

Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer

NCT00084721

COMPLETED Phase 2

Dutasteride in Treating Patients With Recurrent Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy

NCT00403000

COMPLETED Phase 1

Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors

NCT00238225

COMPLETED NA

Fentanyl With or Without Bupivacaine in Reducing Pain in Patients Undergoing Video-Assisted Chest Surgery

NCT00538499

COMPLETED Phase 1

Folate-Depleted Diet Compared With Folate-Supplemented Diet in Preventing Colorectal Cancer in Patients at High Risk for Colorectal Cancer

NCT00096330

COMPLETED Phase 2

Irinotecan and Gemcitabine in Treating Patients With Recurrent or Progressive Stage III or Stage IV Non-Small Cell Lung Cancer

NCT00182806

COMPLETED Phase 1

Irinotecan and Selenium in Treating Patients With Advanced Solid Tumors

NCT00112892

COMPLETED Phase 2

Combination Chemotherapy and Thalidomide in Treating Patients With Stage I, Stage II, or Stage III Multiple Myeloma

NCT00054158

COMPLETED Phase 2

Gemcitabine, Capecitabine, and Bevacizumab in Treating Patients With Metastatic or Unresectable Pancreatic Cancer

NCT00100815

COMPLETED Phase 1

Paricalcitol and Gemcitabine in Treating Patients With Advanced Cancer

NCT00217477

TERMINATED Phase 2

Bevacizumab and Capecitabine as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer

NCT00107315

TERMINATED Phase 2

Fulvestrant in Treating Patients With Recurrent Prostate Cancer

NCT00217464

COMPLETED Phase 2

Lenalidomide With or Without Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

NCT00096044

COMPLETED Phase 1

Photodynamic Therapy Using HPPH in Treating Patients With Stage 0 Non-Small Cell Lung Cancer

NCT00526461

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What is open in the Roswell Park Cancer Institute pipeline

57 recruiting of 365 indexed (16% open); 200 completed (55%).

Phase mix: 7 late (III/IV) vs 238 early (I/II) (early-phase heavy).

Top condition: Leukemia (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Roswell Park Cancer Institute: open-pipeline peers nationwide

Peers matched on 365 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share Roswell Park Cancer InstituteUNC Lineberger Comprehensive Cancer CenterNew York State Psychiatric InstituteUniversity of California, IrvineNorthwell HealthCambridge Health AllianceLouisiana State University Health Sciences Center in New OrleansUniversity of Southern CaliforniaIncyte Corporation
Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 365 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this Roswell Park Cancer Institute page

365 registered trials is a research-attention snapshot, not an endorsement of Roswell Park Cancer Institute or any single study.

  • 57 of Roswell Park Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Leukemia is the condition Roswell Park Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Roswell Park Cancer Institute pipeline card: 365 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.