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NCT00849186 · ClinicalTrials.gov registry record · NA

Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney Cancer

A NA study, sponsored by Roswell Park Cancer Institute.

Completed
Registry status
NA
Development phase
20
Enrollment target

NCT00849186: Completed NA study, sponsored by Roswell Park Cancer Institute.

NCT00849186 is a NA study that has completed, run by Roswell Park Cancer Institute. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00849186, a NA study, has completed, sponsored by Roswell Park Cancer Institute.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving sunitinib before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This clinical trial is studying the side effects of giving sunitinib before surgery and to see how well it works in treating patients with localized or metastatic kidney cancer.

Primary Outcome

Incident Rate: The proportion of the population who experience a grade 3 or higher endpoint-relevant toxic event within 3 months of the beginning of treatment.

Interventions

  • PROCEDURE therapeutic conventional surgery
  • DRUG sunitinib malate
  • PROCEDURE neoadjuvant therapy

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2007-08
Est. Completion 2010-04
Phase NA
Roswell Park Cancer Institute

365 total trials

What the finished NCT00849186 record still lists

NCT00849186 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which therapeutic conventional surgery is the first listed.

NCT00849186 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00849186 about?

NCT00849186 is a clinical study titled "Sunitinib and Surgery in Treating Patients With Localized or Metastatic Kidney Cancer". RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving sunitinib before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This clinical ...

What is the current status of trial NCT00849186?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2007-08. Estimated completion is 2010-04.

What interventions are being tested in trial NCT00849186?

The interventions under investigation include: therapeutic conventional surgery (PROCEDURE), sunitinib malate (DRUG), neoadjuvant therapy (PROCEDURE).

Who is sponsoring clinical trial NCT00849186?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00849186's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00849186, the US trial registry maintained by the National Library of Medicine. NCT00849186 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.