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ClinicalTrials.gov 13 recruiting now early-phase tilt

Recurrent Ovarian Carcinoma: early-phase trial registry

13 of 40 indexed Recurrent Ovarian Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #368 of 28,707 conditions by registered trial count.

40 US clinical trials · 13 currently recruiting · #368 of 28,707 conditions by registered trial count

Recurrent Ovarian Carcinoma: 40 US clinical trials tracked, 13 recruiting.

Recurrent Ovarian Carcinoma is the subject of 40 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 11 of these trials.

Enrollment posture brief

Registry condition recurrent-ovarian-carcinoma

OPEN 13 | RECR 33% | LATE 2 | EARLY 36 | RANK #368 | SPON 11

Nearest open-share peer: COPD (33% recruiting · 86 trials)

Anatomic Stage IIIA Breast C35%Recurrent Ovarian Carcin (th…33%Human Immunodeficiency Virus30%Heart Failure, Congestive12.5%Cocaine Dependence7.5%
Open-enrollment share among volume-matched conditions near Recurrent Ovarian Carcinoma

Recurrent Ovarian Carcinoma lists 13 open slots (33% of 40 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Ovarian Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Ovarian Carcinoma is recruiting below its size-band peers.

    13 of 40 indexed trials (32.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Ovarian Carcinoma research.

    National Cancer Institute (NCI) accounts for 11 of 40 trials (27.5%). 16 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Ovarian Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 40 trials that report a genuine target (sentinel values excluded). 31 of those (77.5%) plan for fewer than 100 participants.

  4. Recurrent Ovarian Carcinoma research is mostly interventional.

    39 interventional and 1 observational studies make up this index (97.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 118Phase 218Phase 32

Open and recent trials

40 total, page 1 of 1

RECRUITING 2,000 participants

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES Study

University of Washington

NCT06295965

RECRUITING Phase 1 300 participants

Serial Imaging of the Novel Radiotracer [^18F] FLuorthanatrace ([^18F] FTT) by PET/CTF

M.D. Anderson Cancer Center

NCT03604315

RECRUITING Phase 2 165 participants

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

National Cancer Institute (NCI)

NCT05554328

RECRUITING Early Phase 1 161 participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Ohio State University Comprehensive Cancer Center

NCT07144826

RECRUITING NA 120 participants

An Automated Personalized Physical Activity Intervention to Improve Immune Function and Clinical Outcomes in Stage II-IV Ovarian, Primary Peritoneal or Fallopian Tube Cancer and Newly Diagnosed Endometrial Cancer, Life on the Go 3 Study

Roswell Park Cancer Institute

NCT06855706

RECRUITING Phase 2 80 participants

Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer

Roswell Park Cancer Institute

NCT05231122

RECRUITING Phase 2 62 participants

ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer

Ira Winer

NCT04055649

RECRUITING Phase 1 40 participants

Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Mayo Clinic

NCT05920798

RECRUITING Phase 2 40 participants

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Rutgers, The State University of New Jersey

NCT03428802

RECRUITING Phase 1 34 participants

Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics

University of Utah

NCT04315233

RECRUITING Phase 2 32 participants

Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer

Jonsson Comprehensive Cancer Center

NCT04469764

RECRUITING Phase 1 24 participants

Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

M.D. Anderson Cancer Center

NCT03968406

RECRUITING Phase 1 12 participants

MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer

Mayo Clinic

NCT06483048

ACTIVE NOT RECRUITING Phase 2 444 participants

Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT02839707

ACTIVE NOT RECRUITING Phase 1 159 participants

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

M.D. Anderson Cancer Center

NCT02208375

ACTIVE NOT RECRUITING Phase 3 150 participants

Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian Cancer

Cordgenics

NCT03949283

ACTIVE NOT RECRUITING Phase 2 96 participants

Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

M.D. Anderson Cancer Center

NCT03579316

ACTIVE NOT RECRUITING Phase 1 88 participants

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

National Cancer Institute (NCI)

NCT01012817

ACTIVE NOT RECRUITING Phase 1 71 participants

Modified Immune Cells (Autologous CAR T Cells) in Treating Patients with Advanced, Recurrent Platinum Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Precigen

NCT03907527

ACTIVE NOT RECRUITING Phase 2 70 participants

Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

National Cancer Institute (NCI)

NCT02595892

ACTIVE NOT RECRUITING Phase 2 62 participants

Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer

National Cancer Institute (NCI)

NCT03348631

ACTIVE NOT RECRUITING Phase 3 50 participants

Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer

National Cancer Institute (NCI)

NCT01081262

ACTIVE NOT RECRUITING Phase 1 50 participants

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

National Cancer Institute (NCI)

NCT02142803

ACTIVE NOT RECRUITING Phase 1 40 participants

Surgery and Chemotherapy With or Without Chemotherapy After Surgery in Treating Patients With Ovarian, Fallopian Tube, Uterine, or Peritoneal Cancer

City of Hope Medical Center

NCT01970722

ACTIVE NOT RECRUITING Phase 2 38 participants

Lenvatinib, Pembrolizumab, and Paclitaxel for Treatment of Recurrent Endometrial, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Floor Backes, MD

NCT04781088

ACTIVE NOT RECRUITING Phase 1 35 participants

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

National Cancer Institute (NCI)

NCT02627443

ACTIVE NOT RECRUITING Phase 1 31 participants

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

M.D. Anderson Cancer Center

NCT03586661

ACTIVE NOT RECRUITING Phase 2 30 participants

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

M.D. Anderson Cancer Center

NCT03449108

ACTIVE NOT RECRUITING Phase 2 22 participants

Pembrolizumab and Carboplatin for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

University of Washington

NCT04387227

ACTIVE NOT RECRUITING Phase 1 9 participants

Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Roswell Park Cancer Institute

NCT03017131

ACTIVE NOT RECRUITING Phase 2 5 participants

Pembrolizumab in Treating Participants With Recurrent Ovarian Cancer

Jonsson Comprehensive Cancer Center

NCT03732950

COMPLETED Phase 2 107 participants

Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer

National Cancer Institute (NCI)

NCT01305213

COMPLETED Phase 1 70 participants

Viral Therapy in Treating Patients With Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer That Did Not Respond to Platinum Chemotherapy

National Cancer Institute (NCI)

NCT00602277

COMPLETED Phase 2 40 participants

Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation

Roswell Park Cancer Institute

NCT02953457

COMPLETED Phase 2 31 participants

A6 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Gynecologic Oncology Group

NCT00939809

COMPLETED Phase 1 29 participants

Pembrolizumab and Carboplatin in Treating Patients With Relapsed or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

University of Washington

NCT03029598

COMPLETED Phase 1 15 participants

Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Primary Ovarian or Uterine Cancer

University of Colorado, Denver

NCT03325634

COMPLETED Phase 2 14 participants

Testing Whether the Combination of Two Immunotherapy Drugs Have Activity in Recurrent or Persistent Clear Cell Ovarian Cancer

National Cancer Institute (NCI)

NCT03602586

COMPLETED Phase 2 13 participants

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Mayo Clinic

NCT02312245

COMPLETED Phase 1 5 participants

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

M.D. Anderson Cancer Center

NCT03318900

Phase Distribution

PhaseTrial count
Phase 1 18
Phase 2 18
Phase 3 2

Named interventions

Most-linked intervention names on Recurrent Ovarian Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
14 trials
Computed Tomography Procedure
7 trials
Pembrolizumab Biological
7 trials
Bevacizumab Biological
6 trials
Biospecimen Collection Procedure
6 trials
Carboplatin Drug
5 trials
Pharmacological Study Other
4 trials
Gemcitabine Hydrochloride Drug
4 trials

US sites by state

Facility locations filed on Recurrent Ovarian Carcinoma trials. A trial with sites in several states counts in each.

California 12 trials
Arizona 11 trials
Texas 10 trials
Florida 8 trials
Pennsylvania 6 trials
Ohio 6 trials
New York 6 trials
Minnesota 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Ovarian Carcinoma page

40 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Ovarian Carcinoma condition card totals 40 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.