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NCT00470184 · ClinicalTrials.gov registry record · Phase 2

Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer

A Phase 2 study, sponsored by Roswell Park Cancer Institute.

Completed
Registry status
Phase 2
Development phase
41
Enrollment target

NCT00470184: Completed Phase 2 study, sponsored by Roswell Park Cancer Institute.

NCT00470184 is a Phase 2 study that has completed, run by Roswell Park Cancer Institute. The registered enrollment target is 41 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (69% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00470184, a Phase 2 study, has completed, sponsored by Roswell Park Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
41 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving chemotherapy together with radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This phase II trial is studying how well giving oxaliplatin and capecitabine together with radiation therapy works in treating patients undergoing surgery for stage II, stage III, or stage IV esophageal cancer.

Interventions

  • GENETIC gene expression analysis
  • GENETIC microarray analysis
  • DRUG oxaliplatin
  • DRUG capecitabine
  • GENETIC reverse transcriptase-polymerase chain reaction

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2006-11
Phase Phase 2
Roswell Park Cancer Institute

365 total trials

What the finished NCT00470184 record still lists

NCT00470184 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (69% lower).

The record links to 0 conditions, and to 5 interventions - of which gene expression analysis is the first listed.

NCT00470184 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00470184 about?

NCT00470184 is a clinical study titled "Oxaliplatin, Capecitabine, and Radiation Therapy in Patients Undergoing Surgery for Stage II, III, IV Esophageal Cancer". RATIONALE: Drugs used in chemotherapy, such as oxaliplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving chemotherapy together with radia...

What is the current status of trial NCT00470184?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2006-11.

What interventions are being tested in trial NCT00470184?

The interventions under investigation include: gene expression analysis (GENETIC), microarray analysis (GENETIC), oxaliplatin (DRUG), capecitabine (DRUG), reverse transcriptase-polymerase chain reaction (GENETIC).

Who is sponsoring clinical trial NCT00470184?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00470184's enrollment target sits among peer trials

41 1352nd of 2000 higher than 639 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00470184, the US trial registry maintained by the National Library of Medicine. NCT00470184 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.