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NCT00524589 · ClinicalTrials.gov registry record · Phase 2

Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy

A Phase 2 study, sponsored by Roswell Park Cancer Institute.

Terminated
Registry status
Phase 2
Development phase
18
Enrollment target

NCT00524589 is a Phase 2 study that was terminated before completion, run by Roswell Park Cancer Institute. The registered enrollment target is 18 participants.

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The verdict

NCT00524589, a Phase 2 study, was terminated before completion, sponsored by Roswell Park Cancer Institute.

TERMINATED
Registry status
Phase 2
Development phase
18 participants
Enrollment target

Study Summary

RATIONALE: Calcitriol may help prostate cancer cells become more like normal cells, and to grow and spread more slowly. Dexamethasone may help calcitriol work better by making tumor cells more sensitive to the drug. Giving calcitriol together with dexamethasone may be an effective treatment for prostate cancer that did not respond to hormone therapy . PURPOSE: This phase II trial is studying how well giving calcitriol together with dexamethasone works in treating patients with prostate cancer that did not respond to hormone therapy.

Interventions

  • GENETIC protein expression analysis
  • OTHER laboratory biomarker analysis
  • DRUG dexamethasone
  • DIETARY_SUPPLEMENT calcitriol

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2006-04
Est. Completion 2010-09
Phase Phase 2

Sponsor

Roswell Park Cancer Institute

365 total trials

What the Registry Record Tells You About NCT00524589

The ClinicalTrials.gov registry entry for NCT00524589 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Roswell Park Cancer Institute, which has 365 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which protein expression analysis is the first listed.

NCT00524589 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00524589 about?

NCT00524589 is a clinical study titled "Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy". RATIONALE: Calcitriol may help prostate cancer cells become more like normal cells, and to grow and spread more slowly. Dexamethasone may help calcitriol work better by making tumor cells more sensitive to the drug. Giving calcitriol together with dexamethasone may be an effective treatment for pros...

What is the current status of trial NCT00524589?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2006-04. Estimated completion is 2010-09.

What interventions are being tested in trial NCT00524589?

The interventions under investigation include: protein expression analysis (GENETIC), laboratory biomarker analysis (OTHER), dexamethasone (DRUG), calcitriol (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT00524589?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.