Roswell Park Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Roswell Park Cancer Institute sits in the top decile of US sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count).

365 total trials 57 currently recruiting 200 completed early-phase tilt top decile by trial count

Roswell Park Cancer Institute: 365 sponsored US clinical trials, 57 recruiting.

Roswell Park Cancer Institute sponsors 365 registered US clinical trials on ClinicalTrials.gov, 57 of them currently recruiting, and 200 completed. 7 of these trials are in Phase 3-4 (later-stage) and 238 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 9 trials.

Top-decile sponsor footprint

Roswell Park Cancer Institute ranks in the top decile of sponsors by registered trial count (#98 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 18/100

200 of 279 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (71.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

365 total, page 2 of 8

RECRUITING Phase 2

Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

NCT04682158

RECRUITING Phase 1

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

NCT03965234

RECRUITING

Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors

NCT04526587

RECRUITING Phase 2

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

NCT04068649

RECRUITING NA

Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors

NCT03880422

RECRUITING Phase 2

Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

NCT04067830

RECRUITING NA

Photoacoustic Imaging of the Breast in Patients With Breast Cancer and Healthy Subjects

NCT03897270

ACTIVE NOT RECRUITING NA

Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers

NCT05825001

ACTIVE NOT RECRUITING Phase 2

Belantamab Mafodotin and Lenalidomide for the Treatment of Multiple Myeloma in Patients With Minimal Residual Disease Positive After Stem Cell Transplant

NCT04876248

ACTIVE NOT RECRUITING Early Phase 1

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

NCT06011772

ACTIVE NOT RECRUITING NA

Implementation of Evidence-Based Strategy (PC TEACH) for the Optimization of HPV Vaccination in Rural Primary Care

NCT06256718

ACTIVE NOT RECRUITING NA

Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial

NCT05338905

ACTIVE NOT RECRUITING NA

A Sugar-Sweetened Beverage Reduction Intervention for Native American Men

NCT06029517

ACTIVE NOT RECRUITING NA

A Pilot Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) in Central Non-Small Cell Lung Cancer

NCT05138900

ACTIVE NOT RECRUITING Phase 1

Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery

NCT03678350

ACTIVE NOT RECRUITING Phase 2

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

NCT04269213

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab Every 12 Weeks Versus Every 3 Weeks in Treating Patients With Non-small Cell Lung Cancer

NCT04032418

ACTIVE NOT RECRUITING Phase 1

Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer

NCT04073745

ACTIVE NOT RECRUITING Phase 2

Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

NCT03899987

ACTIVE NOT RECRUITING NA

rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers

NCT03865472

ACTIVE NOT RECRUITING Early Phase 1

Stereotactic Body Radiation Therapy Followed by Surgery in Treating Patients With Stage I-IIIA Non-small Cell Lung Cancer

NCT03348748

ACTIVE NOT RECRUITING Phase 1

Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT03017131

ACTIVE NOT RECRUITING Phase 1

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT03192397

ACTIVE NOT RECRUITING Phase 1

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

NCT02650986

ACTIVE NOT RECRUITING Phase 1

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

NCT02334865

ACTIVE NOT RECRUITING Phase 1

CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer

NCT02955290

ACTIVE NOT RECRUITING Phase 2

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

NCT02455557

ACTIVE NOT RECRUITING Phase 1

Carfilzomib, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Stage I-IV Diffuse Large B-cell Lymphoma

NCT01959698

ACTIVE NOT RECRUITING Phase 1

Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney Cancer

NCT01684397

NOT YET RECRUITING Phase 2

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

NCT06827054

NOT YET RECRUITING Phase 2

Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer

NCT06943664

NOT YET RECRUITING NA

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers

NCT07553819

NOT YET RECRUITING Phase 1

Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms

NCT07679334

NOT YET RECRUITING Early Phase 1

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

NCT06334016

NOT YET RECRUITING NA

Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy

NCT07075705

NOT YET RECRUITING Phase 2

CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer

NCT07543172

TERMINATED Phase 1

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

NCT06343376

TERMINATED Phase 2

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

NCT04093323

COMPLETED NA

Weight Loss Interventions to Reduce Cancer Progression in Prostate Cancer Patients Under Active Surveillance

NCT05764330

TERMINATED Phase 1

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

NCT05756166

TERMINATED NA

Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography

NCT05876091

COMPLETED NA

Financial Health Educational Program for Increasing Financial Literacy Among Underserved Communities in Western New York

NCT05997589

COMPLETED NA

ivWatch in Prevention of Extravasation of Vesicants in an Oncology Setting

NCT06758011

COMPLETED NA

A Virtual Intervention to Improve Medication Adherence in Pediatric Cancer: MedSupport

NCT05150028

TERMINATED

Consumer Assessment of Tobacco Flavor and Odor

NCT04358315

COMPLETED

Behavioral Parenting Skills As A Novel Target for Improving Pediatric Medication Adherence

NCT05587582

COMPLETED NA

Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems

NCT05423340

TERMINATED Phase 1

Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease

NCT04836429

TERMINATED Phase 1

Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer

NCT05037500

COMPLETED NA

Mindfulness Meditation

NCT05098002

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What is open in the Roswell Park Cancer Institute pipeline

57 recruiting of 365 indexed (16% open); 200 completed (55%).

Phase mix: 7 late (III/IV) vs 238 early (I/II) (early-phase heavy).

Top condition: Leukemia (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Roswell Park Cancer Institute: open-pipeline peers nationwide

Peers matched on 365 registered trials and 16% open enrollment, not the therapeutic-area sidebar.

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share Roswell Park Cancer InstituteUNC Lineberger Comprehensive Cancer CenterNew York State Psychiatric InstituteUniversity of California, IrvineNorthwell HealthCambridge Health AllianceLouisiana State University Health Sciences Center in New OrleansUniversity of Southern CaliforniaIncyte Corporation
Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Roswell Park Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 365 trials (± recruiting share)

Sponsors near 16% open enrollment (± trial volume)

What to do with this Roswell Park Cancer Institute page

365 registered trials is a research-attention snapshot, not an endorsement of Roswell Park Cancer Institute or any single study.

  • 57 of Roswell Park Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Leukemia is the condition Roswell Park Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Leukemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Roswell Park Cancer Institute pipeline card: 365 registered trials from official public datasets.Report a data error.